SDS-PAGE
CD32 / FCGR2B recombinant protein
Recombinant Mouse CD32 / FCGR2B Protein (His & AVI tag), Biotinylated
SDS-PAGE
SDS-PAGE
Description: A DNA sequence encoding the extracellular domain (Met 1-Arg 217) of mouse FGGR2B (NP_001070657.1) as fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
NCBI and Uniprot Product Information
Uniprot Description
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.
Protein type: Cell surface; Membrane protein, integral; Oncoprotein
Chromosomal Location of Human Ortholog: 1 H3|1 78.02 cM
Cellular Component: cell surface; external side of plasma membrane; integral to membrane; integral to plasma membrane; lipid raft; recycling endosome
Molecular Function: IgG binding; immunoglobulin binding; protein binding; receptor signaling protein activity
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cell surface receptor linked signal transduction; defense response; endocytic recycling; immune complex clearance; immune response; immunoglobulin mediated immune response; mast cell activation; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of B cell proliferation; negative regulation of humoral immune response mediated by circulating immunoglobulin; negative regulation of immune response; negative regulation of immunoglobulin production; negative regulation of inflammatory response to antigenic stimulus; negative regulation of interleukin-10 production; negative regulation of neutrophil apoptosis; negative regulation of phagocytosis; negative regulation of type I hypersensitivity; phagocytosis, engulfment; positive regulation of phagocytosis; receptor-mediated endocytosis; response to bacterium
Research Articles on CD32 / FCGR2B
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Product Notes
The CD32 / FCGR2B fcgr2 (Catalog #AAA2547197) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse FGGR2B consists of 212 amino acids and has a predicted molecular mass of 23.9 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm FGGR2B is approximately 38-43 kDa due to glycosylation. Researchers should empirically determine the suitability of the CD32 / FCGR2B fcgr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD32 / FCGR2B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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