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Immunohistochemistry (IHC) (Immunochemical staining FABP6 in mouse small intestine with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)

Rabbit anti-Mouse, Rat FABP6 Polyclonal Antibody | anti-FABP6 antibody

Anti-FABP6 Antibody, Rabbit Polyclonal

Gene Names
Fabp6; GT; ILBP; I-15P; ILBP3; Illbp; I-BABP
Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
FABP6; Polyclonal Antibody; Anti-FABP6 Antibody; Rabbit Polyclonal; FABP6 Antibody; Rabbit PAb; Antigen Affinity Purified; fatty acid binding protein 6; ileal; Anti-GT Antibody; Anti-I-15P Antibody; Anti-I-BABP Antibody; Anti-ILBP Antibody; Anti-ILBP3 Antibody; Anti-Illbp Antibody; anti-FABP6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse FABP6
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-FABP6 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-1:500
Immunogen
A synthetic peptide corresponding to the N-terminus of the Mouse FABP6
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Mouse FABP6, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining FABP6 in mouse small intestine with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)

Immunohistochemistry (IHC) (Immunochemical staining FABP6 in mouse small intestine with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)

Immunohistochemistry (IHC)

(Immunochemical staining FABP6 in rat small intestine with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)

Immunohistochemistry (IHC) (Immunochemical staining FABP6 in rat small intestine with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-FABP6 antibody
Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Isoform2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform1of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform2is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. FABP6/I-BABP is a cancer-related protein that acts as an intracellular transporter of bile acid in the ileal epithelium. FABP6/I-BABP may also play an important role in early carcinogenesis.
References
Kurz M., et al., 2003, Proteins 50:312-328. Ohmachi, T. et al., 2006, Clin Cancer Res.12 (17):5090-5. Fang C., et al., 2007, Cancer Res. 67:9039-9046. Szczerbal, I. et al., 2007, Cytogenet Genome Res.118 (1):63-6.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,486 Da
NCBI Official Full Name
gastrotropin
NCBI Official Synonym Full Names
fatty acid binding protein 6, ileal (gastrotropin)
NCBI Official Symbol
Fabp6
NCBI Official Synonym Symbols
GT; ILBP; I-15P; ILBP3; Illbp; I-BABP
NCBI Protein Information
gastrotropin
UniProt Protein Name
Gastrotropin
Protein Family
UniProt Gene Name
Fabp6
UniProt Synonym Gene Names
Illbp; GT; ILBP

NCBI Description

The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. This protein functions within the ileum, the distal 25-30% of the small intestine, and plays a role in enterohepatic circulation of bile acids and cholesterol homeostasis. In humans, it has been reported that polymorphisms in FABP6 confer a protective effect in obese individuals from developing type 2 diabetes. In mice deficiency of this gene affects bile acid metabolism in a gender-specific manner and was reported to be required for efficient apical to basolateral transport of conjugated bile acids. [provided by RefSeq, Jan 2013]

Uniprot Description

Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (PubMed:23251388). Stimulates gastric acid and pepsinogen secretion ().

Research Articles on FABP6

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Product Notes

The FABP6 fabp6 (Catalog #AAA8103904) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FABP6 Antibody, Rabbit Polyclonal reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FABP6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-1:500. Researchers should empirically determine the suitability of the FABP6 fabp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FABP6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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