Estrogen Receptor a Recombinant Protein
Recombinant Estrogen Receptor a protein
Purity
The purified recombinant protein is greater than 90% homogeneous and contains no detectable protease, DNase and RNase activity.
Synonyms
Estrogen Receptor a; Recombinant Estrogen Receptor a protein; ESR1; ESR; Era; ESRA; ESTRR; NR3A1; Estrogen Receptor a recombinant protein
Host
Baculovirus
Purity/Purification
The purified recombinant protein is greater than 90% homogeneous and contains no detectable protease, DNase and RNase activity.
Form/Format
4ug of Recombinant ER protein and Dilution Buffer AM1 (20mM Tris-Cl (pH8), 20% glycerol, 100mM KCl, 1mM DTT and 0.2mM EDTA).
Protein Species
Human
Tag
His-Tag
Notes
Recombinant ER is suitable for DNA and protein-protein interaction assays. 20-100ng are sufficient for in vitro transcription assays and 100ng are sufficient for protein-protein interaction studies. This protein is not recommended for use in TransAM. NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
Related Product Information for Estrogen Receptor a recombinant protein
Short Description: Recombinant ER is specific for the ER alpha subunit and was expressed from full-length (accession number NM 000125) with an N-terminal His-Tag in a baculovirus system and purified by an affinity column in combination with FPLC chromatography. The purified recombinant protein is greater than 90% homogeneous and contains no detectable protease, DNase and RNase activity. Estrogen receptors (ER) are nuclear hormone receptors that mediate the actions of the endogenous steroid hormone, 17b-estradiol (E2). ER is synthesized as two protein forms, ERa and ERb, which can bind to the estrogen receptor element (ERE) as homo- or heterodimers. Cell proliferation and differentiation triggered by ER activation has been heavily studied in bone-wasting and breast cancer treatments. Estrogen receptors are necessary for sexual development and reproductive function. Recombinant ER is suitable for DNA-protein (gelshift) and protein-protein interaction assays.
Background: Estrogen receptors (ER) are nuclear hormone receptors that mediate the actions of the endogenous steroid hormone, 17b-estradiol (E2). ER is synthesized as two protein forms, ERa and ERb, which can bind to the estrogen receptor element (ERE) as homo- or heterodimers. Cell proliferation and differentiation triggered by ER activation has been heavily studied in bone-wasting and breast cancer treatments. Estrogen receptors are necessary for sexual development and reproductive function.
Background: Estrogen receptors (ER) are nuclear hormone receptors that mediate the actions of the endogenous steroid hormone, 17b-estradiol (E2). ER is synthesized as two protein forms, ERa and ERb, which can bind to the estrogen receptor element (ERE) as homo- or heterodimers. Cell proliferation and differentiation triggered by ER activation has been heavily studied in bone-wasting and breast cancer treatments. Estrogen receptors are necessary for sexual development and reproductive function.
Product Categories/Family for Estrogen Receptor a recombinant protein
NCBI and Uniprot Product Information
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Product Notes
The Estrogen Receptor a (Catalog #AAA388011) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Estrogen Receptor a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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