Protein DGCR14 (Dgcr14) Recombinant Protein | Dgcr14 recombinant protein
Recombinant Mouse Protein DGCR14 (Dgcr14)
Gene Names
Dgcr14; ES2; Dgsi; Ess2; Dgcr1; Es2el; AI462402; D16H22S1269E
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein DGCR14 (Dgcr14); Recombinant Mouse Protein DGCR14 (Dgcr14); Dgcr14 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-479, Full length protein
Sequence
MGTPGTSAGALFLSSASAPSRKRAAGEAGEAGVARSRQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKISREPPPPYVTPATFETPEVHPGSAVLGNKPRPQGRDLDDGEAGEEEEKEPLPSLDVFLSQYTSEDNASFQEIMEVAKEKSHARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQAGVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQIVHKNTRFLRDPFSQALSRSQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPLMTWGEVENTPLRVEGSESPYVDRTPGPTFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSSHLKTPAGGPQTPTSTPAPGSATRTPLTQDPASITDNLLQLPARRKASDFF
Sequence Length
479
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Dgcr14 recombinant protein
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,604 Da
NCBI Official Full Name
splicing factor ESS-2 homolog isoform 2
NCBI Official Synonym Full Names
DiGeorge syndrome critical region gene 14
NCBI Official Symbol
Dgcr14
NCBI Official Synonym Symbols
ES2; Dgsi; Ess2; Dgcr1; Es2el; AI462402; D16H22S1269E
NCBI Protein Information
splicing factor ESS-2 homolog; protein DGCR14
UniProt Protein Name
Splicing factor ESS-2 homolog
Protein Family
UniProt Gene Name
Ess2
UniProt Synonym Gene Names
Dgcr14; Dgsi; Es2; Es2el
NCBI Description
The human ortholog of this gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of human chromosome band 22q11.2. The encoded protein localizes to the nucleus, and the orthologous protein in humans co-purifies with C complex spliceosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
May be involved in pre-mRNA splicing.
Research Articles on Dgcr14
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Product Notes
The Dgcr14 ess2 (Catalog #AAA1199149) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-479, Full length protein. The amino acid sequence is listed below: MGTPGTSAGA LFLSSASAPS RKRAAGEAGE AGVARSRQRV LDEEEYIEGL QTVIQRDFFP DVEKLQAQKE YLEAEENGDL ERMRQIAIKF GSALGKISRE PPPPYVTPAT FETPEVHPGS AVLGNKPRPQ GRDLDDGEAG EEEEKEPLPS LDVFLSQYTS EDNASFQEIM EVAKEKSHAR HAWLYQAEEE FEKRQKDNLE LPSAEHQAIE SSQAGVETWK YKAKNSLMYY PEGVPDEEQL FKKPRQIVHK NTRFLRDPFS QALSRSQLQQ AAALNAQHKQ GKVGPDGKEL IPQESPRVGG FGFVATPSPA PGVNESPLMT WGEVENTPLR VEGSESPYVD RTPGPTFKIL EPGRRERLGL KMANEAAAKN RAKKQEALRR VTENLASLTP KGLSPAMSPA LQRLVSRTAS KYTDRALRAS YTPSPARSSH LKTPAGGPQT PTSTPAPGSA TRTPLTQDPA SITDNLLQLP ARRKASDFF. It is sometimes possible for the material contained within the vial of "Protein DGCR14 (Dgcr14), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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