EMR1 recombinant protein

Human EMR1 Protein, hFc Tag

Cat. Num. AAA188365

• Gene Names: EMR1; TM7LN3
• Purity: Affinity purification
• Synonyms: EMR1; Human EMR1 Protein; hFc Tag; TM7LN3; EMR1 recombinant protein

• Host: HEK293 cells
• Purity/Purification: Affinity purification
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
• Sequence: EMR1 (His21-Asp599) + hFc (Glu99-Ala330)

• Origin: Human
• Reconstitution: Reconstitute with deionized water
• Tag: C-Human Fc
• Preparation and Storage: Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)

Related Product Information for EMR1 recombinant protein

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 372266078
• NCBI GeneID: 2015
• NCBI Accession #: NP_001243181.1
• NCBI GenBank Nucleotide #: NM_001256252.1
• UniProt Accession #: Q14246; Q2I7G5; Q6ZMN0; Q8NGA7; A6NHV2; B7Z486; B7Z489; E7EPX9; E9PD45; H9KV79
• Molecular Weight: 97,683 Da
• NCBI Official Full Name: EGF-like module-containing mucin-like hormone receptor-like 1 isoform 2
• NCBI Official Synonym Full Names: egf-like module containing, mucin-like, hormone receptor-like 1
• NCBI Official Symbol: EMR1
• NCBI Official Synonym Symbols: TM7LN3
• NCBI Protein Information: EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1
• UniProt Protein Name: EGF-like module-containing mucin-like hormone receptor-like 1
• UniProt Gene Name: EMR1
• UniProt Synonym Gene Names: TM7LN3
• UniProt Entry Name: EMR1_HUMAN

NCBI Description

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion