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Immunohistochemistry (IHC) (Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human ADGRE1 / F4/80 Polyclonal Antibody | anti-ADGRE1 antibody

Anti-ADGRE1 / F4/80 Antibody (aa811-860) IHC-plus

Gene Names
ADGRE1; EMR1; TM7LN3
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
ADGRE1 / F4/80; Polyclonal Antibody; Anti-ADGRE1 / F4/80 Antibody (aa811-860) IHC-plus; Rabbit Polyclonal (IgG) to Human ADGRE1 / F4/80; Human ADGRE1 / F4/80; EMR1 hormone receptor; F4/80; EGF-like module receptor 1; TM7LN3; EMR1; anti-ADGRE1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
EMR1 antibody detects endogenous levels of EMR1.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
886
Applicable Applications for anti-ADGRE1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:10000)
IHC-P (5 ug/ml)
WB (1:500 - 1:1000)
Immunogen
ADGRE1 / F4/80 antibody was raised against synthetic peptide derived from human EMR1 (aa811-860).
Immunogen Description
Synthetic peptide derived from human EMR1 (aa811-860).
Immunogen Type
Synthetic peptide
Antigen Modification
aa811-860
Target Species
Human
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of the lysates from HUVEC cells using Anti-EMR1 / F4/80 Antibody.)

Western Blot (WB) (Western blot analysis of the lysates from HUVEC cells using Anti-EMR1 / F4/80 Antibody.)
Related Product Information for anti-ADGRE1 antibody
ADGRE1 Antibody, EMR1 hormone receptor Antibody, F4/80 Antibody, EGF-like module receptor 1 Antibody, TM7LN3 Antibody, EMR1 Antibody Description: ADGRE1 / EMR1 / F4/80 is a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
82,771 Da
NCBI Official Full Name
adhesion G protein-coupled receptor E1 isoform 1
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor E1
NCBI Official Symbol
ADGRE1
NCBI Official Synonym Symbols
EMR1; TM7LN3
NCBI Protein Information
adhesion G protein-coupled receptor E1
UniProt Protein Name
Adhesion G protein-coupled receptor E1
UniProt Gene Name
ADGRE1
UniProt Entry Name
AGRE1_HUMAN

NCBI Description

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 2

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: external side of plasma membrane; integral to plasma membrane

Molecular Function: calcium ion binding; G-protein coupled receptor activity

Biological Process: adaptive immune response; cell adhesion; cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway

Research Articles on ADGRE1

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Product Notes

The ADGRE1 adgre1 (Catalog #AAA2400021) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ADGRE1 / F4/80 Antibody (aa811-860) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADGRE1 / F4/80 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:10000) IHC-P (5 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the ADGRE1 adgre1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADGRE1 / F4/80, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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