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Eukaryotic Translation Initiation Factor 3I Recombinant Protein | EIF3I recombinant protein

Recombinant Human Eukaryotic Translation Initiation Factor 3I, Sf9

Gene Names
EIF3I; TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta
Purity
>90.0% as determined by SDS-PAGE.
Synonyms
Eukaryotic Translation Initiation Factor 3I; Recombinant Human Eukaryotic Translation Initiation Factor 3I; Sf9; eIF3-beta; eIF3-p36; EIF3S2; PRO2242; TRIP-1; TRIP1; Eukaryotic translation initiationfactor 3 subunit I; eIF3i; TGF-beta receptor-interacting protein 1; eIF-3-beta; EIF3I Human; Eukaryotic Translation Initiation Factor 3I Human Recombinant; EIF3I recombinant protein
Ordering
For Research Use Only!
Host
Sf9, Baculovirus Cells
Purity/Purification
>90.0% as determined by SDS-PAGE.
Form/Format
Sterile filtered colorless solution.
EIF3I protein solution (0.25mg/ml) 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 40% Glycerol and 1mM DTT.
Sequence
Amino acid: MKPILLQGHE RSITQIKYNR EGDLLFTVAK DPIVNVWYSVngERLGTYMG HTGAVWCVDADWDTKHVLTG SADNSCRLWD CETGKQLALL KTNSAVRTCG FDFGGNIIMF STDKQMGYQCFVSFFDLRDP SQIDNNEPYM KIPCNDSKIT SAVWGPLGEC IIAGHESGEL NQYSAKSGEVLVNVKEHSRQ INDIQLSRDM TMFVTASKDN TAKLFDSTTL EHQKTFRTER PVNSAALSPNYDHVVLGGGQ EAMDVTTTST RIGKFEARFF HLAFEEEFGR VKGHFGPINS VAFHPDGKSY SSGGEDGYVR IHYFDPQYFE FEFEAHHHHH H.
Sequence Length
325
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Related Product Information for EIF3I recombinant protein
Introduction: Eukaryotic translation initiation factor 3, subunit I (EIF3I) is part of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is essential for numerous steps in the initiation of protein synthesis. The eIF-3 complex links with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP: methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also essential for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Among the diseases associated with EIF3I are clonorchiasis, and tonsillitis.

Description: EIF3I Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 331 amino acids (1-325 a.a) and having a molecular mass of 37.3kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).EIF3I is fused to an 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for EIF3I recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
eukaryotic translation initiation factor 3 subunit I
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 3 subunit I
NCBI Official Symbol
EIF3I
NCBI Official Synonym Symbols
TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta
NCBI Protein Information
eukaryotic translation initiation factor 3 subunit I
UniProt Protein Name
Eukaryotic translation initiation factor 3 subunit I
UniProt Gene Name
EIF3I
UniProt Entry Name
EIF3I_HUMAN

Uniprot Description

eIF3-beta: eukaryotic translation initiation factor 3 subunit 2. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. eIF-3 is composed of at least 12 different subunits. Phosphorylated by TGF-beta type II receptor.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: eukaryotic translation initiation factor 3 complex; cytosol

Molecular Function: protein binding; translation initiation factor activity

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation

Research Articles on EIF3I

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Product Notes

The EIF3I eif3i (Catalog #AAA141420) is a Recombinant Protein produced from Sf9, Baculovirus Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Amino acid: MKPILLQGHE RSITQIKYNR EGDLLFTVAK DPIVNVWYSV ngERLGTYMG HTGAVWCVDA DWDTKHVLTG SADNSCRLWD CETGKQLALL KTNSAVRTCG FDFGGNIIMF STDKQMGYQC FVSFFDLRDP SQIDNNEPYM KIPCNDSKIT SAVWGPLGEC IIAGHESGEL NQYSAKSGEV LVNVKEHSRQ INDIQLSRDM TMFVTASKDN TAKLFDSTTL EHQKTFRTER PVNSAALSPN YDHVVLGGGQ EAMDVTTTST RIGKFEARFF HLAFEEEFGR VKGHFGPINS VAFHPDGKSY SSGGEDGYVR IHYFDPQYFE FEFEAHHHHH H. It is sometimes possible for the material contained within the vial of "Eukaryotic Translation Initiation Factor 3I, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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