Eukaryotic Translation Initiation Factor 1A X-linked Recombinant Protein | EIF1AX recombinant protein
Recombinant Human Eukaryotic Translation Initiation Factor 1A X-linked
Gene Names
EIF1AX; EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Eukaryotic Translation Initiation Factor 1A X-linked; Recombinant Human Eukaryotic Translation Initiation Factor 1A X-linked; EIF1AX Human; Eukaryotic Translation Initiation Factor 1 X-linked Human Recombinant; eukaryotic translation initiation factor 1A; X-linked; eIF-4C; EIF1A; EIF4C; eIF-1A; EIF1AP1; EIF1AX recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The EIF1AX protein solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH8.0) containing 5mM DTT, 200mM NaCl and 40% glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAM CFDGVKRLCH IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT FGPGDDDEIQ FDDIGDDDED IDDI
Sequence Length
144
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for EIF1AX recombinant protein
Description: EIF1AX Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 150 amino acids (1-144a.a.) and having a molecular wieght of 18.6kDa. EIF1AX is fused to 20a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: EIF1AX is an important eukaryotic translation initiation factor. EIF1AX is essential for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5'' end of capped RNA. EIF1AP1 is needed for maximal rate of protein biosynthesis. EIF1AX increases ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA (I) to 40 S ribosomal subunits.
Introduction: EIF1AX is an important eukaryotic translation initiation factor. EIF1AX is essential for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5'' end of capped RNA. EIF1AP1 is needed for maximal rate of protein biosynthesis. EIF1AX increases ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA (I) to 40 S ribosomal subunits.
Product Categories/Family for EIF1AX recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,460 Da
NCBI Official Full Name
eukaryotic translation initiation factor 1A, X-chromosomal
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 1A, X-linked
NCBI Official Symbol
EIF1AX
NCBI Official Synonym Symbols
EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
NCBI Protein Information
eukaryotic translation initiation factor 1A, X-chromosomal; Putative eukaryotic translation initiation factor 1A; eIF-1A X isoform; eukaryotic translation initiation factor 1A, X chromosome; eukaryotic translation initiation factor 4C
UniProt Protein Name
Eukaryotic translation initiation factor 1A, X-chromosomal
Protein Family
UniProt Gene Name
EIF1AX
UniProt Synonym Gene Names
EIF1A; EIF4C; eIF-1A X isoform; eIF-4C
UniProt Entry Name
IF1AX_HUMAN
NCBI Description
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
Uniprot Description
EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family
Protein type: Translation initiation; Translation; RNA-binding
Chromosomal Location of Human Ortholog: Xp22.12
Cellular Component: cytosol
Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity
Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression
Research Articles on EIF1AX
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Product Notes
The EIF1AX eif1ax (Catalog #AAA144316) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAM CFDGVKRLCH IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT FGPGDDDEIQ FDDIGDDDED IDDI. It is sometimes possible for the material contained within the vial of "Eukaryotic Translation Initiation Factor 1A X-linked, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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