Rabbit eIF1A Polyclonal Antibody | anti-EIF1AX antibody

eIF1A Rabbit pAb

Cat. Num. AAA4751932

• Gene Names: EIF1AX; EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
• Purity: Affinity purified
• Synonyms: eIF1A; Polyclonal Antibody; eIF1A Rabbit pAb; Eukaryotic translation initiation factor 1A; X-chromosomal; EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1; anti-EIF1AX antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: Supplied in 50nM Tris-Glycine (pH7.4), 0.15M Nacl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

• Applicable Applications for anti-EIF1AX antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
• Application Notes: WB: 1:2000-1:10,000; IHC: 1:20; ICC/IF: 1:20; IP: 1:20
• Immunogen: A synthetic peptide of human eIF1A
• Conjugation: Unconjugated
• Modification: Unmodification
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot detection of eIF1A in K562,C6,3T3,Hela cell lysates using eIF1A Rabbit pAb(1:1000 diluted). Predicted band size:17kDa. Observed band size:17kDa.)

Related Product Information for anti-EIF1AX antibody

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

NCBI and Uniprot Product Information

• NCBI GI #: 4503499
• NCBI GeneID: 1964
• NCBI Accession #: NP_001403.1
• NCBI GenBank Nucleotide #: NM_001412.3
• UniProt Accession #: P47813; Q0VGC2; Q5JPS5; Q5JPS6; B2R5U5
• Molecular Weight: 16,460 Da
• NCBI Official Full Name: eukaryotic translation initiation factor 1A, X-chromosomal
• NCBI Official Synonym Full Names: eukaryotic translation initiation factor 1A, X-linked
• NCBI Official Symbol: EIF1AX
• NCBI Official Synonym Symbols: EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
• NCBI Protein Information: eukaryotic translation initiation factor 1A, X-chromosomal; Putative eukaryotic translation initiation factor 1A; eIF-1A X isoform; eukaryotic translation initiation factor 1A, X chromosome; eukaryotic translation initiation factor 4C
• UniProt Protein Name: Eukaryotic translation initiation factor 1A, X-chromosomal
• Protein Family: Eukaryotic translation initiation factor
• UniProt Gene Name: EIF1AX
• UniProt Synonym Gene Names: EIF1A; EIF4C; eIF-1A X isoform; eIF-4C
• UniProt Entry Name: IF1AX_HUMAN

NCBI Description

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]

Uniprot Description

EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family

Protein type: Translation initiation; Translation; RNA-binding

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: cytosol

Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression