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Testing Data (Carrier:pET30a-CHAPV-NP-His(C-term) Virus:Chapare virus strain 810419 segment S, complete sequence)

Chapare mammarenavirus Nucleocapsid (CHAPV-NP) Protein | CHAPV-NP protein

Chapare mammarenavirus Nucleocapsid Protein (CHAPV-NP)

Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Synonyms
Chapare mammarenavirus Nucleocapsid (CHAPV-NP); Chapare mammarenavirus Nucleocapsid Protein (CHAPV-NP); CHAPV-NP protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Form/Format
Soluble protein; PBS, PH=7.4
Tag
His-tag
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Carrier:pET30a-CHAPV-NP-His(C-term) Virus:Chapare virus strain 810419 segment S, complete sequence)

Testing Data (Carrier:pET30a-CHAPV-NP-His(C-term) Virus:Chapare virus strain 810419 segment S, complete sequence)
Related Product Information for CHAPV-NP protein
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Source of Infection

NCBI and Uniprot Product Information

Molecular Weight
1686bp;47kDa

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Product Notes

The CHAPV-NP (Catalog #AAA3015998) is a Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Chapare mammarenavirus Nucleocapsid (CHAPV-NP), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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