MIP-3 beta (CCL19) active protein
Mouse MIP-3 beta (CCL19)
Gene Names
Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC analysis
Synonyms
MIP-3 beta (CCL19); Mouse MIP-3 beta (CCL19); Recombinant Murine MIP-3 beta (CCL19); MIP-3 beta (CCL19) active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC analysis
Form/Format
Lyophilized
Sequence
GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRG YQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Sequence Length
108
Endotoxin Level
< 0.1 ng per ug of CCL19
Biological Activity
Determined by its ability to chemoattract human mature dendritic cells using a concentration range of 10.0-100.0 ng/ml.
Related Product Information for MIP-3 beta (CCL19) active protein
MIP-3beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3beta is active on murine cells. Mouse urine MIP-3beta is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Product Categories/Family for MIP-3 beta (CCL19) active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9.2 kDa
NCBI Official Full Name
C-C motif chemokine 19
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 19
NCBI Official Symbol
Ccl19
NCBI Official Synonym Symbols
ELC; CKb11; MIP3B; Scya19; exodus-3
NCBI Protein Information
C-C motif chemokine 19; chemokine CCL19; EBI1 ligand chemokine; EBI1-ligand chemokine; EBI-1 ligand chemokine; small inducible cytokine A19; small-inducible cytokine A19; EBV-induced molecule 1 ligand chemokine; epstein-Barr virus-induced molecule 1 ligand chemokine
UniProt Protein Name
C-C motif chemokine 19
UniProt Gene Name
Ccl19
UniProt Synonym Gene Names
Elc; Scya19; EBI1 ligand chemokine; ELC
UniProt Entry Name
CCL19_MOUSE
Uniprot Description
Function: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Subcellular location: Secreted.
Tissue specificity: Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus.
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on MIP-3 beta (CCL19)
Similar Products
Product Notes
The MIP-3 beta (CCL19) ccl19 (Catalog #AAA691881) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse MIP-3 beta (CCL19) reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRG YQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS. It is sometimes possible for the material contained within the vial of "MIP-3 beta (CCL19), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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