Testing Data
RANTES active protein
Rat RANTES (CCL5)
Gene Names
Ccl5; Scya5; Rantes
Reactivity
Species Reactivity: RatCross Reactivity: Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
RANTES; Rat RANTES (CCL5); Recombinant Rat RANTES (CCL5); RANTES active protein
Host
E Coli
Reactivity
Species Reactivity: Rat
Cross Reactivity: Human
Cross Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
SPYGSDTTP CCFAYLSLA LPRAHVKEY FYTSSKCSN LAVVFVTRR NRQVCANPE KKWVQEYIN YLEMS
Biological Activity
Assay#1: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration range of 50.0-100.0 ng/ml. Assay#2: Determined by its ability to chemoattract human blood monocy
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for RANTES active protein
RANTES is a protein which has been shown to be a chemoattractant for peripheral blood monocytes. It appears to selectively attract T cells of the CD4+/CD45RO+ phenotype in vitro. Recombinant Rat RANTES is a 7.9 kDa protein containing 68 amino acid residues.
Product Categories/Family for RANTES active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
10,170 Da
NCBI Official Full Name
C-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 5
NCBI Official Symbol
Ccl5
NCBI Official Synonym Symbols
Scya5; Rantes
NCBI Protein Information
C-C motif chemokine 5; SIS-delta; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES; regulated upon activation normal T-cell expressed and secreted
UniProt Protein Name
C-C motif chemokine 5
UniProt Gene Name
Ccl5
UniProt Synonym Gene Names
Scya5
UniProt Entry Name
CCL5_RAT
NCBI Description
may play a role in cellular response to viral infection in testicular somatic cells [RGD, Feb 2006]
Uniprot Description
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
Research Articles on RANTES
1. Expression of RANTES and CCR5 in cardiac allografts may play important roles in chronic rejection.
Similar Products
Product Notes
The RANTES ccl5 (Catalog #AAA696059) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Rat RANTES (CCL5) reacts with Species Reactivity: Rat Cross Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SPYGSDTTP CCFAYLSLA LPRAHVKEY FYTSSKCSN LAVVFVTRR NRQVCANPE KKWVQEYIN YLEMS. It is sometimes possible for the material contained within the vial of "RANTES, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
