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Components (We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse CSNK1A1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot.)

CSNK1A1 sirna

CSNK1A1 siRNA (Mouse)

Gene Names
Csnk1a1; CK1a; Csnk1a; 2610208K14Rik; 4632404G05Rik; 5430427P18Rik
Reactivity
Mouse
Applications
RNA Interference (RNAi)
Purity
> 97%
Synonyms
CSNK1A1; CSNK1A1 siRNA (Mouse); Casein kinase I isoform alpha; CKI-alpha; CK1; CSNK1A1 sirna
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Mouse
Specificity
CSNK1A1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Sequence Length
337
Applicable Applications for CSNK1A1 sirna
RNA Interference (RNAi)
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Preparation and Storage
Store at -20°C for one year.

Components

(We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse CSNK1A1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot.)

Components (We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse CSNK1A1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot.)

Directions for Use

(We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).)

Directions for Use (We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).)
Related Product Information for CSNK1A1 sirna
siRNA to inhibit CSNK1A1 expression using RNA interference

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
casein kinase I isoform alpha isoform X7
NCBI Official Synonym Full Names
casein kinase 1, alpha 1
NCBI Official Symbol
Csnk1a1
NCBI Official Synonym Symbols
CK1a; Csnk1a; 2610208K14Rik; 4632404G05Rik; 5430427P18Rik
NCBI Protein Information
casein kinase I isoform alpha
UniProt Protein Name
Casein kinase I isoform alpha
Protein Family
UniProt Gene Name
Csnk1a1
UniProt Synonym Gene Names
CKI-alpha
UniProt Entry Name
KC1A_MOUSE

Uniprot Description

CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation.

Protein type: EC 2.7.11.1; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CK1 group; CK1 family

Cellular Component: kinetochore; centrosome; cytoskeleton; membrane; cytoplasm; nuclear speck; mRNA cleavage and polyadenylation specificity factor complex; chromosome; ribonucleoprotein complex; nucleus; chromosome, pericentric region

Molecular Function: transferase activity; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; magnesium ion binding; nucleotide binding; phosphoprotein binding; kinase activity; glycoprotein binding; peptide binding; ATP binding; protein kinase activity

Biological Process: mitosis; regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; cell division; cell morphogenesis; cell cycle; phosphorylation; protein amino acid phosphorylation; phagocytosis

Research Articles on CSNK1A1

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Product Notes

The CSNK1A1 csnk1a1 (Catalog #AAA828614) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The CSNK1A1 siRNA (Mouse) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CSNK1A1 can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the CSNK1A1 csnk1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSNK1A1, siRNA" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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