Prolactin Active Protein | PRL active protein
Human Prolactin
Reactivity
Human
Purity
> 95% by SDS-PAGE and HPLC analysis
Synonyms
Prolactin; Human Prolactin; Recombinant Human Prolactin; PRL active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 95% by SDS-PAGE and HPLC analysis
Form/Format
Lyophilized
Sequence
MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYT HGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR S WNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQ VHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HK IDNYLKLL KCRIIHNNNC
Sequence Length
227
Endotoxin Level
< 0.1 ng per ug of Prolactin
Biological Activity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.
Related Product Information for PRL active protein
Prolactin, also known as mammotrophin, luterotropic hormone, and lutetropin, is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant human Prolactin is a 23 kDa globular protein containing 200 amino acid residues.
Product Categories/Family for PRL active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23 kDa
NCBI Official Full Name
prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
PRL
NCBI Protein Information
prolactin; decidual prolactin
UniProt Protein Name
Prolactin
Protein Family
UniProt Gene Name
PRL
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_HUMAN
NCBI Description
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Uniprot Description
Function: Prolactin acts primarily on the mammary gland by promoting lactation.
Subcellular location: Secreted.
Sequence similarities: Belongs to the somatotropin/prolactin family.
Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.
Research Articles on PRL
Similar Products
Product Notes
The PRL prl (Catalog #AAA691738) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Prolactin reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYT HGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR S WNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQ VHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HK IDNYLKLL KCRIIHNNNC. It is sometimes possible for the material contained within the vial of "Prolactin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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