Prolactin Active Protein | PRL active protein

Prolactin, rat recombinant

Cat. Num. AAA845161

• Gene Names: Prl; PRLB; Prol; PRLSD1; Prl1a1; RNPROL; RATPRLSD1
• Applications: SDS-Page
• Purity: >=95%
• Synonyms: Prolactin; rat recombinant; Mammotropin; Luterotropic hormone; Lutetropin; Prlr; PRL; luteotropic hormone; LTH; PRLR; PRL-R; PRL R; PRL active protein

• Host: E Coli
• Purity/Purification: >=95%
• Form/Format: Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 8.0 + 50 mM NaCl. ; Appearance: Lyophilized protein
• Sequence Length: 226

• Applicable Applications for PRL active protein: SDS-PAGE; HPLC
• Solubility/Reconstitution Instructions: Reconstitute in H?O to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers
• Endotoxin Level: <0.1 ng/mug
• Biological Activity: The ED?? determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 cells was found to be in the range of 0.1-1.0 ng/ml.
• Results: 0.1-1.0 ng/ml
• Handling: Centrifuge the vial prior to opening.
• Preparation and Storage: At -20 degree C; Shelf Life: 12 months

Testing Data

Related Product Information for PRL active protein

Background: Prolactin (also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant murine Prolactin is a 22.5 kDa globular protein containing 198 amino acid residues.

NCBI and Uniprot Product Information

• NCBI GI #: 6981404
• NCBI GeneID: 24683
• NCBI Accession #: NP_036761.1
• NCBI GenBank Nucleotide #: NM_012629.1
• UniProt Accession #: P01237; P70520
• Molecular Weight: 22.5 kDa
• NCBI Official Full Name: prolactin
• NCBI Official Synonym Full Names: prolactin
• NCBI Official Symbol: Prl
• NCBI Official Synonym Symbols: PRLB; Prol; PRLSD1; Prl1a1; RNPROL; RATPRLSD1
• NCBI Protein Information: prolactin
• UniProt Protein Name: Prolactin
• Protein Family: Prolactin
• UniProt Gene Name: Prl
• UniProt Synonym Gene Names: PRL
• UniProt Entry Name: PRL_RAT

NCBI Description

induces lactation; may facilitate decidual growth and placentation; promotes prostate epithelial cell proliferation [RGD, Feb 2006]

Uniprot Description

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Motility/polarity/chemotaxis; Secreted; Cytokine; Secreted, signal peptide

Cellular Component: extracellular region; secretory granule

Molecular Function: prolactin receptor binding; hormone activity

Biological Process: lactation; response to drug; circadian rhythm; maternal behavior; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; response to organic cyclic substance; response to estradiol stimulus; cellular response to hormone stimulus; ovulation cycle; regulation of JAK-STAT cascade; response to ethanol; mammary gland development; positive regulation of cell proliferation; parturition; regulation of ossification; multicellular organismal response to stress; response to nutrient; positive regulation of epithelial cell proliferation; STAT protein nuclear translocation