Dynamin-1 ELISA Kit | DNM1 elisa kit
Phospho-Dynamin-1 (Ser778) Colorimetric Cell-Based ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
DYN1: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within the presynaptic compartment and may participate in specialized neuronal functions such as rapid synaptic vesicle recycling. Part of a protein network that controls nucleation of actin from membranes. Contains one PH domain.
Protein type: EC 3.6.5.5; Hydrolase; Microtubule-binding; Motility/polarity/chemotaxis; Motor; Vesicle
Chromosomal Location of Human Ortholog: 9q34.11
Cellular Component: extracellular exosome; Golgi apparatus; membrane coat; microtubule; mitochondrial membrane; myelin sheath; photoreceptor inner segment; plasma membrane; synaptic vesicle
Molecular Function: D2 dopamine receptor binding; GTP binding; GTPase activity; identical protein binding; microtubule binding; nitric-oxide synthase binding; protein binding; protein C-terminus binding; protein complex binding; protein dimerization activity; protein kinase binding; RNA binding
Biological Process: adult locomotory behavior; dynamin family protein polymerization involved in mitochondrial fission; endocytosis; endosome organization and biogenesis; ephrin receptor signaling pathway; G-protein coupled receptor internalization; mitochondrial fission; protein tetramerization; receptor-mediated endocytosis; sensory perception of sound; synaptic transmission, GABAergic; synaptic vesicle budding from presynaptic endocytic zone membrane; toxin transport
Disease: Epileptic Encephalopathy, Early Infantile, 31
Research Articles on DNM1
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Product Notes
The Human, Mouse, Rat DNM1 dnm1 (Catalog #AAA9501655) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501655 ELISA Kit recognizes Human, Mouse, Rat DNM1. It is sometimes possible for the material contained within the vial of "Dynamin-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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