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Structure

Fostriecin sodium Biochemical

Fostriecin sodium

Purity
>=98% by HPLC
Synonyms
Fostriecin sodium; (6R)-5; 6-Dihydro-6-[ (1E; 3R; 4R; 6R; 7Z; 9Z; 11E)-3; 6; 13-trihydroxy-3-methyl-4- (phosphonooxy)-1; 7; 9; 11-tridecatetraenyl]-2H-pyran-2-one sodium salt; Fostriecin sodium biochemical
Ordering
For Research Use Only!
Purity/Purification
>=98% by HPLC
Form/Format
Colorless solid
Salt Form
Yes
CAS Number
87860-39-7
Cell-Permeable
Yes
Reconstitution
Water (>30 mg/ml)
SMILES
CC(C=CC1CC=CC(=O)O1)(C(CC(C=CC=CC=CCO)O)OP(=O)(O)[O-])O.[Na+]
InChi
InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
InChi Key
XBUIKNRVGYFSHL-IAVQPKKASA-M
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.

Structure

Structure
Related Product Information for Fostriecin sodium biochemical
Fostriecin is a potent inhibitor of the serine/threonine protein phosphatases PP2A and PP4 with IC50 value of 3.2 and 3 nM; respectively. It also displays weak inhibition of topoisomerase II having IC50 of 40 muM and PP1 with IC50 of 131 muM. Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo.

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Product Notes

The Fostriecin sodium (Catalog #AAA846383) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Fostriecin sodium, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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