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Typical Testing Data/Standard Curve (for reference only)

Rat Deoxyribonuclease gamma ELISA Kit | Dnase1l3 elisa kit

Rat Deoxyribonuclease gamma ELISA Kit

Reactivity
Rat
Synonyms
Deoxyribonuclease gamma; Rat Deoxyribonuclease gamma ELISA Kit; DNase gamma; DNaseY; Deoxyribonuclease I-like 3; DNase I-like 3; Dnase1l3; Dnase1l3 elisa kit
Ordering
For Research Use Only!
Reactivity
Rat
Sequence Length
310
Assay Type
Sandwich
Detection Range
0.312-20 ng/mL
Sensitivity
0.184 ng/mL
Intra-Assay CV
<=4.7%
Inter-Assay CV
<=8.6%
Recovery
106%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,708 Da
NCBI Official Full Name
deoxyribonuclease gamma
NCBI Official Synonym Full Names
deoxyribonuclease 1-like 3
NCBI Official Symbol
Dnase1l3
NCBI Protein Information
deoxyribonuclease gamma
UniProt Protein Name
Deoxyribonuclease gamma
Protein Family
UniProt Gene Name
Dnase1l3
UniProt Synonym Gene Names
DNase gamma; DNase I-like 3
UniProt Entry Name
DNSL3_RAT

NCBI Description

Ca2+/Mg2+ dependent endonuclease that catalyzes cleavage of both single and double stranded DNA; may play a role in apoptotic DNA fragmentation [RGD, Feb 2006]

Uniprot Description

Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (PubMed:7957253). Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated microparticles and thus suppresses anti-DNA autoimmunity ().

Research Articles on Dnase1l3

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Product Notes

The Rat Dnase1l3 dnase1l3 (Catalog #AAA289885) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289885 ELISA Kit recognizes Rat Dnase1l3. It is sometimes possible for the material contained within the vial of "Deoxyribonuclease gamma, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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