Western Blot (WB)
()
DJ1 recombinant protein
DJ1 protein
Applications
ELISA, SDS-Page, Western Blot
Purity
> 95% pure
Synonyms
DJ1; DJ1 protein; Oncogene DJ1 protein; Parkinson disease 7 protein; DJ 1 protein; DJ-1 protein; DJ1 recombinant protein
Host
Human
Purity/Purification
> 95% pure
Form/Format
Supplied in liquid form in PBS buffer with 20 mM GSH
Sequence Length
378
Applicable Applications for DJ1 recombinant protein
ELISA (EIA), SDS-PAGE, Western Blot (WB)
Protein Type
Recombinant
Biological Significance
DJ1 protects cells against oxidative stress and cell death. DJ1 plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. DJ1 may act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Stabilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7B and inhibits its deubiquitinating activity.
Expression System
E Coli
Preparation and Storage
Store at 4 degree C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 degree C, avoid repeat freeze/thaw cycles
Western Blot (WB)
()
Western Blot (WB)
()
Related Product Information for DJ1 recombinant protein
Purified recombinant DJ1 protein
Product Categories/Family for DJ1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
47 kDa
NCBI Official Full Name
DJ1
UniProt Protein Name
DJ1
UniProt Gene Name
dj1
UniProt Entry Name
D1MJ50_CRYPA
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Product Notes
The DJ1 dj1 (Catalog #AAA5303989) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DJ1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the DJ1 dj1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DJ1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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