Typical Testing Data/Standard Curve (for reference only)
Mouse Endoribonuclease Dicer ELISA Kit | Dicer1 elisa kit
Mouse Endoribonuclease Dicer ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
DICER1: a cytoplasmic type-III RNase that plays a central role in RNA interference (RNAi) pathways to produce the active small RNAs that represses gene expression. Possesses a DEAD box RNA helicase motif in its amino terminus and a dsRNA-binding motif in the carboxy terminus. Dicer, along with Ago2 andTRBP, are the main components of the RNA-induced silencing complex (RISC). Fragile X syndrome repeats form RNA hairpins that are cut by Dicer but do not activate the interferon-inducible protein kinase, PKR. Four alternatively spliced isoforms have been described.
Protein type: Helicase; Cell development/differentiation; Ribonuclease; RNA-binding; EC 3.1.26.3; RNA processing
Cellular Component: axon; cytoplasm; dendrite; ER-Golgi intermediate compartment; growth cone; nucleus
Molecular Function: ATP binding; deoxyribonuclease I activity; DNA binding; double-stranded RNA binding; endonuclease activity; endoribonuclease activity; endoribonuclease activity, producing 5'-phosphomonoesters; helicase activity; hydrolase activity; metal ion binding; miRNA binding; nuclease activity; nucleotide binding; protein binding; protein domain specific binding; ribonuclease III activity; RNA binding; siRNA binding
Biological Process: anatomical structure development; angiogenesis; branching morphogenesis of a tube; cardiac muscle cell development; cartilage development; cell proliferation; cerebral cortex development; defense response to virus; DNA fragmentation during apoptosis; embryonic hindlimb morphogenesis; embryonic limb morphogenesis; epidermis morphogenesis; gut development; hair follicle development; hair follicle morphogenesis; inner ear receptor cell development; lung development; meiotic spindle organization and biogenesis; miRNA-mediated gene silencing, miRNA loading onto RISC; miRNA-mediated gene silencing, production of miRNAs; mRNA stabilization; multicellular organism growth; myelin formation in the peripheral nervous system; myoblast cell differentiation involved in skeletal muscle regeneration; negative regulation of transcription from RNA polymerase II promoter; nerve development; neurite morphogenesis; olfactory bulb interneuron differentiation; positive regulation of myelination; positive regulation of Schwann cell differentiation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; pre-microRNA processing; regulation of cell cycle; regulation of cell differentiation; regulation of gene expression; regulation of myelination; regulation of neurogenesis; regulation of neuron differentiation; regulation of Notch signaling pathway; regulation of odontogenesis of dentine-containing teeth; regulation of oligodendrocyte differentiation; regulation of protein amino acid phosphorylation; regulation of RNA metabolic process; regulation of viral genome replication; reproductive structure development; RNA interference, conversion of ds siRNA to ss siRNA; RNA interference, production of siRNA; RNA interference, siRNA loading onto RISC; RNA interference, targeting of mRNA for destruction; RNA processing; RNA-mediated gene silencing; rRNA catabolic process; spinal cord motor neuron differentiation; spindle assembly; spleen development; stem cell maintenance; zygote asymmetric cell division
Research Articles on Dicer1
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Product Notes
The Mouse Dicer1 dicer1 (Catalog #AAA2880664) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880664 ELISA Kit recognizes Mouse Dicer1. It is sometimes possible for the material contained within the vial of "Endoribonuclease Dicer, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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