Diacylglycerol kinase theta (DGKQ) Recombinant Protein | DGKQ recombinant protein

Recombinant Human Diacylglycerol kinase theta (DGKQ) , partial

• Gene Names: DGKQ; DAGK; DAGK4; DAGK7
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Diacylglycerol kinase theta (DGKQ); Recombinant Human Diacylglycerol kinase theta (DGKQ); partial; DGKQ recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 942

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for DGKQ recombinant protein

This protein contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction.

NCBI and Uniprot Product Information

• NCBI GI #: 40806175
• NCBI GeneID: 1609
• NCBI Accession #: NP_001338.2
• NCBI GenBank Nucleotide #: NM_001347.3
• UniProt Accession #: P52824; Q6P3W4
• Molecular Weight: 101,155 Da
• NCBI Official Full Name: diacylglycerol kinase theta
• NCBI Official Synonym Full Names: diacylglycerol kinase theta
• NCBI Official Symbol: DGKQ
• NCBI Official Synonym Symbols: DAGK; DAGK4; DAGK7
• NCBI Protein Information: diacylglycerol kinase theta
• UniProt Protein Name: Diacylglycerol kinase theta
• Protein Family: Diacylglycerol kinase
• UniProt Gene Name: DGKQ
• UniProt Synonym Gene Names: DAGK4; DAG kinase theta; DGK-theta

NCBI Description

The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. [provided by RefSeq, Jul 2008]

Uniprot Description

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.