Human DCP1 decapping enzyme homolog A (S. cerevisiae) ELISA Kit | DCP1A elisa kit
Human mRNA-decapping enzyme 1A, DCP1A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Uniprot Description
DCP1A: a decapping enzyme. Plays a role in general and regulated mRNA decay. Apparently plays a role in the nonsense-mediated decay pathway that rids cells of mRNAs containing premature termination codons. May function as a transactivator of SMAD4 that participates in TGF-beta signaling.
Protein type: RNA processing; Transcription, coactivator/corepressor; Hydrolase; EC 3.-.-.-
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: membrane; nucleus; cytosol
Molecular Function: identical protein binding; protein binding; hydrolase activity
Biological Process: mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA catabolic process, deadenylation-dependent decay
Research Articles on DCP1A
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Product Notes
The Human DCP1A dcp1a (Catalog #AAA9320896) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320896 ELISA Kit recognizes Human DCP1A. It is sometimes possible for the material contained within the vial of "DCP1 decapping enzyme homolog A (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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