Cytokeratin 20, CK20 Recombinant Protein | CK20 recombinant protein
Cytokeratin 20, CK20 Protein (Active)
Applications
ELISA, SDS-Page
Purity
>95% by SDS-PAGE
Synonyms
Cytokeratin 20; CK20; CK20 Protein (Active); Keratin type I cytoskeletal 20; Cytokeratin-20; CK-20; Keratin-20; K20; KRT20; CK20 recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid
Concentration
0.5 mg/ml (varies by lot)
Applicable Applications for CK20 recombinant protein
ELISA (EIA), SDS-PAGE
Storage buffer
Each vial contains Tris-HCL (pH7.4 ± 0.2) with 0.2% sodium azide.
Preparation and Storage
Ship at 4 degree C. Upon receipt, aliquot and store at -20 degree C or -80 degree C for long term. Avoid repeated freeze and thaw cycles
Related Product Information for CK20 recombinant protein
Recombinant full length human Cytokeratin 20 protein with molecular weight 46.6 kDa.
Keratin 20, also called Cytokeratin 20, CK20, is a protein that in humans is encoded by the KRT20 gene. KRT20 has an apparent molecular mass of about 46 kD. It is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. KRT20 formed heterotypic complexes with KRT8 in vitro, and the complexes assembled into intermediate filaments under appropriate conditions. The protein is commonly found in colorectal cancer, transitional cell carcinomas and in Merkel cell tumours, but is absent in lung cancer, prostate cancer, and non-mucinous ovarian cancer. It is often used in combination with antibodies to CK7 to distinguish different types of glandular tumour.
Keratin 20, also called Cytokeratin 20, CK20, is a protein that in humans is encoded by the KRT20 gene. KRT20 has an apparent molecular mass of about 46 kD. It is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. KRT20 formed heterotypic complexes with KRT8 in vitro, and the complexes assembled into intermediate filaments under appropriate conditions. The protein is commonly found in colorectal cancer, transitional cell carcinomas and in Merkel cell tumours, but is absent in lung cancer, prostate cancer, and non-mucinous ovarian cancer. It is often used in combination with antibodies to CK7 to distinguish different types of glandular tumour.
References
1. Moll R, Schiller DL, Franke WW (August 1990). "Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns". J. Cell Biol. 111 (2): 567-80. 2. Moll, R., Schiller, D. L., Franke, W. W. Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J. Cell Biol. 111: 567-580, 1990. 3. Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M (2003). Manual of Diagnostic Cytology (2 ed.). Greenwich Medical Media, Ltd. pp. 171-172.
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Product Notes
The CK20 (Catalog #AAA355586) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cytokeratin 20, CK20 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), SDS-PAGE. Researchers should empirically determine the suitability of the CK20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 20, CK20, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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