Guinea Pig CXC-chemokine receptor 1 ELISA Kit | CXCR1 elisa kit

Guinea pig CXC-chemokine receptor 1 ELISA Kit

Gene Names

CXCR1; C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1

Reactivity

Guinea Pig

Synonyms

CXC-chemokine receptor 1; Guinea pig CXC-chemokine receptor 1 ELISA Kit; CXCR1 elisa kit

Ordering
Cat. Num. AAA731451 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Guinea Pig

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Assay Type

Competitive

Detection Range

0.5-10ng/mL

Sensitivity

0.1ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Product Categories/Family for CXCR1 elisa kit

Immunology

NCBI and Uniprot Product Information

NCBI GI #

62911779

NCBI GeneID

3577

Molecular Weight

39,791 Da

NCBI Official Full Name

CXCR1

NCBI Official Synonym Full Names

chemokine (C-X-C motif) receptor 1

NCBI Official Symbol

CXCR1

NCBI Official Synonym Symbols

C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1

NCBI Protein Information

C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A

UniProt Protein Name

C-X-C chemokine receptor type 1

Protein Family

C-X-C chemokine receptor

UniProt Gene Name

CXCR1

UniProt Synonym Gene Names

CMKAR1; IL8RA; CXC-R1; CXCR-1; IL-8R A

UniProt Entry Name

CXCR1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

Uniprot Description

IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, cytokine; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; receptor internalization; dendritic cell chemotaxis; inflammatory response; chemotaxis

Disease: Human Immunodeficiency Virus Type 1, Susceptibility To

Research Articles on CXCR1

1. IL-8 induces autocrine signaling via an apical CXCR1 in intestinal epithelial cells.

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Product Notes

The Guinea Pig CXCR1 cxcr1 (Catalog #AAA731451) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA731451 ELISA Kit recognizes Guinea Pig CXCR1. It is sometimes possible for the material contained within the vial of "CXC-chemokine receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Guinea Pig CXC-chemokine receptor 1 ELISA Kit | CXCR1 elisa kit