NCBI Description
This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Jul 2008]
Uniprot Description
CXCL14: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted, signal peptide; Chemokine; Secreted; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q31
Cellular Component: Golgi apparatus; extracellular space
Molecular Function: chemokine activity
Biological Process: cell-cell signaling; immune response; chemotaxis; signal transduction; negative regulation of myoblast differentiation; inner ear development
Product Notes
The Mouse CXCL9 cxcl14 (Catalog #
AAA034534) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA034534 ELISA Kit recognizes Mouse CXCL9.
It is sometimes possible for the material contained within the vial of
"Chemokine C-X-C-Motif Ligand 9, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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