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Cathepsin G Recombinant Protein | CATG recombinant protein

Recombinant mouse Cathepsin G

Gene Names
Ctsg; VSP; CatG
Reactivity
Mouse
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Cathepsin G; Recombinant mouse Cathepsin G; Vimentin-specific protease; VSP; CATG recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Mouse
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Sequence Positions
Full Length, 21-261aa
Tag Info
His-SUMO-tag
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for CATG recombinant protein
This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movent and mitosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42.88kD
NCBI Official Full Name
cathepsin G preproprotein
NCBI Official Synonym Full Names
cathepsin G
NCBI Official Symbol
Ctsg
NCBI Official Synonym Symbols
VSP; CatG
NCBI Protein Information
cathepsin G
UniProt Protein Name
Cathepsin G
Protein Family
UniProt Gene Name
Ctsg
UniProt Synonym Gene Names
VSP

NCBI Description

This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015]

Uniprot Description

CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family.

Protein type: EC 3.4.21.20; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 14 C3|14 28.19 cM

Cellular Component: extracellular matrix; extracellular space; nucleus; plasma membrane; secretory granule; stress granule

Molecular Function: heparin binding; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: antibacterial humoral response; defense response to fungus; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; positive regulation of immune response; protein amino acid phosphorylation; proteolysis; response to lipopolysaccharide

Research Articles on CATG

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Product Notes

The CATG ctsg (Catalog #AAA9420152) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 21-261aa. The Recombinant mouse Cathepsin G reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Cathepsin G, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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