SDS-PAGE
Cystatin 7 / CST7 Recombinant Protein | CST7 recombinant protein
Recombinant Mouse Cystatin 7 / CST7 Protein (Fc tag)
Gene Names
Cst7; Cmap
Purity
> 93 % as determined by SDS-PAGE
Synonyms
Cystatin 7 / CST7; Recombinant Mouse Cystatin 7 / CST7 Protein (Fc tag); CST7; CST7 recombinant protein
Host
Human Cells
Purity/Purification
> 93 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 25mM Tris, 0.15M NaCl, pH 7.5
Sequence Length
144
Application Notes
The recombinant mouse CST7 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 367 amino acids and has a predicted molecular mass of 41.4 KDa. The apparent molecular mass of the protein is approximately 42 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Ala 19
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for CST7 recombinant protein
Background: The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain type s of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new identification and prevention approach of certain human carcinomas metastasis.
Description: A DNA sequence encoding the mouse CST7 (O89098) (Met1-Gln144) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Description: A DNA sequence encoding the mouse CST7 (O89098) (Met1-Gln144) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,380 Da
NCBI Official Full Name
cystatin-F
NCBI Official Synonym Full Names
cystatin F (leukocystatin)
NCBI Official Symbol
Cst7
NCBI Official Synonym Symbols
Cmap
NCBI Protein Information
cystatin-F
UniProt Protein Name
Cystatin-F
Protein Family
UniProt Gene Name
Cst7
UniProt Synonym Gene Names
CMAP
Uniprot Description
CST7: Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system. Belongs to the cystatin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2|2 G3
Cellular Component: extracellular space
Molecular Function: cysteine protease inhibitor activity; protease binding
Research Articles on CST7
Similar Products
Product Notes
The CST7 cst7 (Catalog #AAA2547083) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse CST7 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 367 amino acids and has a predicted molecular mass of 41.4 KDa. The apparent molecular mass of the protein is approximately 42 KDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the CST7 cst7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cystatin 7 / CST7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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