SDS-Page
(Recombinant SARS-CoV-2 NSP1 protein gel 12.5% SDS-PAGE with Coomassie blue staining MW: 19.78 kDa Purity: >90%)
COVID 19 NSP1 Coronavirus Recombinant Protein | COVID-19 recombinant protein
Recombinant SARS-CoV-2 NSP1 protein
Synonyms
COVID 19 NSP1 Coronavirus; Recombinant SARS-CoV-2 NSP1 protein; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; NSP1; COVID-19 recombinant protein
Host
E Coli
Form/Format
Recombinant SARS-CoV-2 NSP1 protein is supplied in 25mM Tris-HCl pH8.0, 300mM NaCl, 10% glycerol and 0.5mM TCEP
Protein Species
SARS-CoV-2
Notes
Recombinant SARS-CoV-2 NSP1 protein is suitable for use in the study of SARS-CoV-2. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for this product is shown.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Shipping Temp: Dry Ice
Shipping Temp: Dry Ice
SDS-Page
(Recombinant SARS-CoV-2 NSP1 protein gel 12.5% SDS-PAGE with Coomassie blue staining MW: 19.78 kDa Purity: >90%)
SDS-Page
(Recombinant SARS-CoV-2 NSP1 protein gel 12.5% SDS-PAGE with Coomassie blue staining MW: 19.78 kDa Purity: >90%)
Related Product Information for COVID-19 recombinant protein
Short Description: Recombinant SARS-CoV-2 NSP1 protein was expressed in E Coli as the full-length protein (accession number YP_009725297.1) with a C-terminal Biotinylation Tag and a C-terminal 6xHis-tag. The predicted molecular weight of the protein is 19.78 kDa. Recombinant SARS-CoV-2 NSP1 protein is suitable for use in the study of SARS-CoV-2.
Background: Coronavirus replication and transcription machinery involves multiple virus-encoded nonstructural proteins (nsp). Coronaviruses are enveloped positive-stranded RNA viruses with the largest currently known RNA genomes. Expression of their genomes begins with the translation of two large replicase polyproteins, pp1a (>4,000 residues) and pp1ab (>7,000 residues), which are encoded by the viral replicase gene that comprises open reading frame 1a (orf1a) and orf1b1. pp1a and pp1ab are extensively processed by orf1a-encoded proteases to yield 15 or 16 mature nonstructural (replicase) proteins that assemble to form the membrane-associated viral replication and transcription machinery, which is vital to the viral life cycle. SARS-CoV-2 NSP1 (Nonstructural Protein 1) is one of the nonstructural proteins encoded by SARS-CoV-2 orf1ab. The polyproteins of CoVs are cleaved by virus-encoded cysteine proteinases comprise papain- and chymotrypsin-like proteases into 16 nonstructural proteins including the expression of NSP1 to NSP11 by orf1a and encoding NSP12 to NSP16 by orf1b. According to reports, is highly conserved, crucial to the virus replication, survival in the society and spread among susceptible populations, and can be a potential virulence factor in COVID-19 through accelerating the cellular RNA degradation and consequently blocking the human immune response. The amino acid sequence of NSP1 is highly conserved among SARS-CoVs..
Background: Coronavirus replication and transcription machinery involves multiple virus-encoded nonstructural proteins (nsp). Coronaviruses are enveloped positive-stranded RNA viruses with the largest currently known RNA genomes. Expression of their genomes begins with the translation of two large replicase polyproteins, pp1a (>4,000 residues) and pp1ab (>7,000 residues), which are encoded by the viral replicase gene that comprises open reading frame 1a (orf1a) and orf1b1. pp1a and pp1ab are extensively processed by orf1a-encoded proteases to yield 15 or 16 mature nonstructural (replicase) proteins that assemble to form the membrane-associated viral replication and transcription machinery, which is vital to the viral life cycle. SARS-CoV-2 NSP1 (Nonstructural Protein 1) is one of the nonstructural proteins encoded by SARS-CoV-2 orf1ab. The polyproteins of CoVs are cleaved by virus-encoded cysteine proteinases comprise papain- and chymotrypsin-like proteases into 16 nonstructural proteins including the expression of NSP1 to NSP11 by orf1a and encoding NSP12 to NSP16 by orf1b. According to reports, is highly conserved, crucial to the virus replication, survival in the society and spread among susceptible populations, and can be a potential virulence factor in COVID-19 through accelerating the cellular RNA degradation and consequently blocking the human immune response. The amino acid sequence of NSP1 is highly conserved among SARS-CoVs..
Product Categories/Family for COVID-19 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 22.7 kDa
Actual Protein Molecular Mass: 25 kDa
Actual Protein Molecular Mass: 25 kDa
NCBI Official Full Name
leader protein
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Product Notes
The COVID-19 (Catalog #AAA389359) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "COVID 19 NSP1 Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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