Mouse anti-Human Catenin, beta-like 1 Monoclonal Antibody | anti-CTNNBL1 antibody

Catenin, beta-like 1 (Beta Catenin-like 1, Beta Catenin-like Protein 1, 5730471K09Rik, Catenin beta-like 1, CTNNBL1, Chromosome 20 Open Reading Frame 3, C20orf33, dJ633O20.1, FLJ21108, Nuclear-associated Protein, Nuclear Protein NAP, NAP, NYD SP19, NYD-SP

Cat. Num. AAA605361

• Gene Names: CTNNBL1; NAP; P14L; PP8304; C20orf33; FLJ21108; NYD-SP19; dJ633O20.1
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Catenin; beta-like 1; Monoclonal Antibody; beta-like 1 (Beta Catenin-like 1; Beta Catenin-like Protein 1; 5730471K09Rik; Catenin beta-like 1; CTNNBL1; Chromosome 20 Open Reading Frame 3; C20orf33; dJ633O20.1; FLJ21108; Nuclear-associated Protein; Nuclear Protein NAP; NAP; NYD SP19; NYD-SP; Anti -Catenin; anti-CTNNBL1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 9j28
• Specificity: Recognizes human CTNNBL1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.4, 1% BSA and 0.05% sodium azide.

• Applicable Applications for anti-CTNNBL1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Synthetic peptide corresponding to the N-terminal region of human CTNNBL1
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-CTNNBL1 antibody

Antibodies; Abs to Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 56204101
• NCBI GeneID: 56259
• UniProt Accession #: Q8WYA6; Q0VAL9; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q96KD2; Q9H7A5; Q0VAM0
• Molecular Weight: 65,173 Da
• NCBI Official Full Name: catenin, beta like 1
• NCBI Official Synonym Full Names: catenin, beta like 1
• NCBI Official Symbol: CTNNBL1
• NCBI Official Synonym Symbols: NAP; P14L; PP8304; C20orf33; FLJ21108; NYD-SP19; dJ633O20.1
• NCBI Protein Information: beta-catenin-like protein 1; OTTHUMP00000030939; OTTHUMP00000030940; nuclear associated protein; nuclear-associated protein; testis development protein NYD-SP19
• UniProt Protein Name: Beta-catenin-like protein 1
• Protein Family: Beta-catenin-like protein
• UniProt Gene Name: CTNNBL1
• UniProt Synonym Gene Names: C20orf33
• UniProt Entry Name: CTBL1_HUMAN

NCBI Description

The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. [provided by RefSeq]

Uniprot Description

CTNNBL1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 20q11.23-q12

Cellular Component: nucleoplasm; spliceosome; membrane; cytoplasm; nucleus

Molecular Function: protein binding; enzyme binding

Biological Process: nuclear mRNA splicing, via spliceosome; somatic diversification of immunoglobulins; apoptosis; positive regulation of apoptosis; RNA splicing; gene expression