Cyclic nucleotide-gated ion channel 2 (CNGC2) Recombinant Protein | CNGC2 recombinant protein

Recombinant Arabidopsis thaliana Cyclic nucleotide-gated ion channel 2 (CNGC2) , partial

• Gene Names: DND1; ATCNGC2; CNGC2; CYCLIC NUCLEOTIDE GATED CHANNEL 2; CYCLIC NUCLEOTIDE-GATED CHANNEL 2; DEFENSE NO DEATH 1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cyclic nucleotide-gated ion channel 2 (CNGC2); Recombinant Arabidopsis thaliana Cyclic nucleotide-gated ion channel 2 (CNGC2); partial; CNGC2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 726

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 15242291
• NCBI GeneID: 831393
• NCBI Accession #: NP_197045.1
• NCBI GenBank Nucleotide #: NM_121545.5
• UniProt Accession #: O65718
• Molecular Weight: 83,241 Da
• NCBI Official Full Name: Cyclic nucleotide-regulated ion channel family protein
• NCBI Official Symbol: DND1
• NCBI Official Synonym Symbols: ATCNGC2; CNGC2; CYCLIC NUCLEOTIDE GATED CHANNEL 2; CYCLIC NUCLEOTIDE-GATED CHANNEL 2; DEFENSE NO DEATH 1
• NCBI Protein Information: Cyclic nucleotide-regulated ion channel family protein
• UniProt Protein Name: Cyclic nucleotide-gated ion channel 2
• Protein Family: Cyclic nucleotide-gated ion channel
• UniProt Gene Name: CNGC2
• UniProt Synonym Gene Names: DND1; AtCNGC2

NCBI Description

'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens.

Uniprot Description

Acts as cyclic nucleotide-gated ion channel. Permeable to potassium and calcium in a cyclic nucleotide-dependent fashion (cAMP or cGMP). Could also transport lithium, cesium and rubium and displays a strong selectivity against sodium. Seems to directly participate in pathogen-induced calcium influx. May function in homeostasis, re-establishing ionic balance after defense action and/or other stimuli. Could mediate the initiation of the developmentally regulated cell death programs.