SDS-PAGE
CFHR1 recombinant protein
Recombinant Human CFHR1 Protein (His tag)
SDS-PAGE
SDS-PAGE
Description: A DNA sequence encoding the human CFHR1 (Q03591) (Met1-Arg330) was expressed with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009]
Uniprot Description
CFHR1: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q31.3
Cellular Component: extracellular space
Biological Process: complement activation
Disease: Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1; Macular Degeneration, Age-related, 1
Research Articles on CFHR1
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Product Notes
The CFHR1 cfhr1 (Catalog #AAA2545451) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human CFHR1 consists of 323 amino acids and predicts a molecular mass of 37.2 KDa. It migrates as an approximately 45 KDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CFHR1 cfhr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CFHR1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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