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Centrin-3 Recombinant Protein | CETN3 recombinant protein

Recombinant Human Centrin-3

Gene Names
CETN3; CEN3; CDC31
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Centrin-3; Recombinant Human Centrin-3; CETN3 Human; Centrin-3 Human Recombinant; CEN3; CEN-3; CETN-3; CETN3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
CETN3 Human 0.5mg/ml solution contains 20mM Trsi HCL pH-8, 0.1M NaCl and 10% glycerol.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKILKDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI
Sequence Length
153
Preparation and Storage
CETN3 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for CETN3 recombinant protein
Description: CETN3 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 187 amino acids (1-167 a.a.) and having a molecular mass of 21.7 kDa. CETN3 protein is fused to a 20 amino acid His-Tag at N-terminus and purified by standard chromatography.

Introduction: CETN3 comprises of 4 EF-hand calcium binding domains, and is a part of the centrin protein family. CETN3 protein is widely expressed cytoskeletal components that demonstrate increased expression during cell differentiation. CETN3 takes part in centrosome reproduction.
Product Categories/Family for CETN3 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,550 Da
NCBI Official Full Name
centrin-3 isoform 3
NCBI Official Synonym Full Names
centrin, EF-hand protein, 3
NCBI Official Symbol
CETN3
NCBI Official Synonym Symbols
CEN3; CDC31
NCBI Protein Information
centrin-3; CDC31 yeast homolog; EF-hand superfamily member; centrin, EF-hand protein, 3 (CDC31 homolog, yeast)
UniProt Protein Name
Centrin-3
Protein Family
UniProt Gene Name
CETN3
UniProt Synonym Gene Names
CEN3
UniProt Entry Name
CETN3_HUMAN

NCBI Description

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Uniprot Description

CETN3: Plays a fundamental role in microtubule-organizing center structure and function. Belongs to the centrin family.

Chromosomal Location of Human Ortholog: 5q14.3

Cellular Component: centriole; centrosome; nucleolus

Molecular Function: calcium ion binding

Biological Process: mitosis; cell division; centrosome cycle

Research Articles on CETN3

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Product Notes

The CETN3 cetn3 (Catalog #AAA143084) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEINQEEFI AIMTGDI. It is sometimes possible for the material contained within the vial of "Centrin-3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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