TIAM1 cdna clone
TIAM1 cDNA Clone
Synonyms
TIAM1; TIAM1 cDNA Clone; TIAM1 cdna clone
Sequence
atgggaaacgcagaaagtcaacatgtagagcacgagttttatggagaaaagcatgccagcctggggcgcaagcacacttcccgctccctgcgcctctcgcacaagacgcggaggaccaggcacgcttcctcggggaaggtgatccacaggaactccgaagtgagcacccgatccagcagcacccccagcatcccccagtccctggctgaaaatggcctggagcccttctcccaagatggtaccctagaagacttcgggagccccatctgggtggaccgagtggacatgggcttgagacctgtgtcttacactgactcttctgtcactcccagcgtagacagcagcatcgtcctcacagcagcctctgtgcagagcatgccagacactgaggagagcaggctttacggggatgacgctacatatttggctgagggaggcaggaggcagcattcctatacatccaatgggcccactttcatggagacggcgagctttaagaagaaacgctccaaatctgcagacatctggcgggaggacagcctggaattctcactctctgatctgagccaagaacatttaacaagcaacgaagaaatcttgggttccgccgaagagaaggactgcgaggaggctcgggggatggaaacgcgggcgagtccgcggcagctcagcacctgtcagagagccaattccttgggtgacttgtatgctcagaaaaactctggagtgacagcaaacggggggccggggagcaaatttgcaggctactgtcggaatttggtgtctgatattcccaatcttgcaaaccataagatgccaccagctgctgctgaagagactcctccgtacagtaattataacacacttccctgtaggaaatctcactgtctctctgaaggtgccaccaacccacaaattagccatagcaacagcatgcaaggcagaagagctaaaacaactcaggatgttaatgcaggcgagggcagtgagtttgcagacagtgggattgaaggggccactaccgacacggacctcctgtccaggcgatctaatgccaccaactccagctactcacccaccacaggccgggcctttgtgggcagcgacagcggcagcagctccaccggggatgcggctcgtcagggggtgtacgagaacttccggcgggagctggagatgagcaccaccaacagcgagagcctggaggaggccggctcggcgcacagcgatgagcagagcagcggcaccctgagctctccgggccagtcggacatcctgctgaccgccgcacagggcacggtgcgcaaggccggcgccctggccgtcaagaacttcctggtgcacaagaagaacaagaaggtggagtcagccacccggaggaagtggaagcactactgggtgtccctgaaaggatgcacgctatttttctacgagagcgacggcaggtctgggatagaccacaacagcatccccaaacacgccgtctgggtggagaacagcattgtgcaggcggtgcctgagcaccccaagaaggactttgtcttctgcctcagcaattccctgggtgatgccttcctttttcagaccactagccagacggagcttgaaaactggatcaccgccatccactctgcctgcgccactgcggtcgcgaggcaccaccacaaggaagacacgctccgactcctgaaatcagagatcaaaaaactggaacagaagattgacatggatgaaaagatgaagaaaatgggtgaaatgcagctgtcttcagtcactgactcaaagaaaaagaaaacaatattagatcagatctttgtctgggagcaaaatctcgagcagttccaaatggacctgtttcgtttccgctgttatttagccagccttcagggtggggagctgccaaaccccaaaaggcttctcgcttttgcaagtcgaccaacgaaagtggccatgggccgccttggaatcttttcggtatcatcgtttcatgccctggtggcagcacgcactggtgaaactggagtgagaagacgtactcaggccatgtccagatccgcgagcaagcgaaggagcaggttttcttctctgtggggtctggatactacctccaaaaagaagcagggacggccaagcatcaatcaggtgtttggagagggaaccgaagctgtaaagaaatctttagagggaatatttgatgacattgttccagatggcaagagggagaaagaagtggtcttacctaacgttcaccagcacaaccctgactgcgacatttgggtccacgagtatttcactccatcctggttctgtctgcccaataatcagcctgccctgacggtcgtccggccaggcgacactgcacgggacaccctggagctgatttgcaagacacatcaactggatcattctgctcattacctgcgcctgaaatttctaatagaaaacaaaatgcagctctatgttccacagcccgaggaagacatctatgagctgctgtacaaagaaattgaaatctgtccaaaagtcactcagagcatccacattgagaagtcagatacagctgctgatacttacgggttttcactttcttctgtggaagaagatggtattcgaaggctgtacgtgaatagtgtgaaggaaaccggtttagcttccaagaaaggcctgaaagcaggagatgagattcttgagatcaataatcgtgctgctgacgccctgaactcttctatgctcaaagatttcctctcacagccctcgctgggcctcctggtgaggacctaccccgagctggaggaaggagtggagctgctggaaagcccgccccaccgagtggacggccctgccgaccttggcgagagccccctcgcctttctcaccagcaacccagggcacagcctttgcagcgagcagggcagcagtgctgagaccgctccagaggagaccgaggggccagacttggaatcctcagatgagactgatcacagcagcaagagtacagaacaggtggccgcattttgccgcagtttgcatgagatgaacccctctgaccagagcccatctcctcaggactccacggggcctcagctggcgaccatgagacaactctcggatgcagataagctgcgcaaggtgatctgcgagctcctggagacggagcgcacctacgtgaaggatttaaactgtcttatggagagatacctaaagcctcttcaaaaagaaacttttctcacccaggatgagcttgacgtgctttttggaaatttaacggaaatggtagagtttcaagtagaattccttaaaactctagaagatggagtgagactggtacctgatttggaaaagcttgagaaggttgatcaatttaagaaagtgctgttctctctggggggatcattcctgtattatgctgaccgcttcaagctctacagtgccttctgcgccagccacacaaaagttcccaaggtcctggtgaaagccaagacagacacggctttcaaggcattcttggatgcccagaacccgaagcagcagcactcatccacgctggagtcgtacctcatcaagcccatccagaggatcctcaagtacccacttctgctcagggagctgttcgccctgaccgatgcggagagcgaggagcactaccacctggacgtggccatcaagaccatgaacaaggttgccagtcacatcaatgagatgcagaaaatccatgaagagtttggggctgtgtttgaccagctgattgctgaacagactggtgagaaaaaagaggttgcagatctgagcatgggagacctgcttttgcacactaccgtgatctggctgaacccgccggcctcgctgggcaagtggaaaaaggaaccagagttggcagcattcgtcttcaaaactgctgtggtccttgtgtataaagatggttccaaacagaagaagaaacttgtaggatctcacaggctttccatttatgaggactgggaccccttcagatttcgacacatgatccccacggaagcgctgcaggttcgagctttggcgagtgcagatgcagaggcaaatgccgtgtgtgaaattgtccatgtaaaatccgagtctgaagggaggccggagagggtctttcacttgtgctgcagctccccagagagccgaaaggatttcctaaaggctgtgcattcaatcctgcgtgataagcacagaagacagctcctcaaaaccgagagccttccctcatcccagcaatatgtcccttttggaggcaaaagattgtgtgcactgaagggggccaggccggccatgagcagggcagtgtctgccccaagcaagtctcttgggaggaggaggcggcggctggctcgaaacaggtttaccattgattctgatgccgtctccgcaagcagcccggagaaagagtcccagcagccccccggtggtggggacactgaccgatgggtagaggagcagtttgatcttgctcagtatgaggagcaagatgacatcaaggagacagacatcctcagtgacgatgatgagttctgtgagtccgtgaagggtgcctcagtggacagagacctgcaggagcggcttcaggccacctccatcagtcagcgggaaagaggccggaaaaccctggatagtcacgcgtcccgcatggcacagctcaagaagcaagctgccctgtcggggatcaatggaggcctggagagcgcaagcgaggaagtcatttgggttaggcgtgaagactttgccccctccaggaaactgaacactgagatctga
Sequence Length
4776
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
170,580 Da
NCBI Official Full Name
Homo sapiens T-cell lymphoma invasion and metastasis 1, mRNA
NCBI Official Synonym Full Names
T-cell lymphoma invasion and metastasis 1
NCBI Official Symbol
TIAM1
NCBI Protein Information
T-lymphoma invasion and metastasis-inducing protein 1
UniProt Protein Name
T-lymphoma invasion and metastasis-inducing protein 1
Protein Family
UniProt Gene Name
TIAM1
UniProt Synonym Gene Names
TIAM-1
UniProt Entry Name
TIAM1_HUMAN
Uniprot Description
TIAM1: modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Regulates migration, cell-matrix and cell-cell adhesion by modulating the actin cytoskeleton through the GTPase, Rac1. Binding to Rac1 and the Arp2/3 complex may drive actin polymerization at specific sites, thus inducing dynamic morphological changes.
Protein type: GEFs; GEFs, Rac/Rho; Oncoprotein; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 21q22.11
Cellular Component: cytosol; extrinsic to internal side of plasma membrane; intercellular junction; plasma membrane
Molecular Function: guanyl-nucleotide exchange factor activity; kinase binding; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity
Biological Process: cell migration; cell-matrix adhesion; ephrin receptor signaling pathway; positive regulation of apoptosis; positive regulation of protein binding; Rac protein signal transduction; regulation of small GTPase mediated signal transduction
Research Articles on TIAM1
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Product Notes
The TIAM1 tiam1 (Catalog #AAA1270499) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggaaacg cagaaagtca acatgtagag cacgagtttt atggagaaaa gcatgccagc ctggggcgca agcacacttc ccgctccctg cgcctctcgc acaagacgcg gaggaccagg cacgcttcct cggggaaggt gatccacagg aactccgaag tgagcacccg atccagcagc acccccagca tcccccagtc cctggctgaa aatggcctgg agcccttctc ccaagatggt accctagaag acttcgggag ccccatctgg gtggaccgag tggacatggg cttgagacct gtgtcttaca ctgactcttc tgtcactccc agcgtagaca gcagcatcgt cctcacagca gcctctgtgc agagcatgcc agacactgag gagagcaggc tttacgggga tgacgctaca tatttggctg agggaggcag gaggcagcat tcctatacat ccaatgggcc cactttcatg gagacggcga gctttaagaa gaaacgctcc aaatctgcag acatctggcg ggaggacagc ctggaattct cactctctga tctgagccaa gaacatttaa caagcaacga agaaatcttg ggttccgccg aagagaagga ctgcgaggag gctcggggga tggaaacgcg ggcgagtccg cggcagctca gcacctgtca gagagccaat tccttgggtg acttgtatgc tcagaaaaac tctggagtga cagcaaacgg ggggccgggg agcaaatttg caggctactg tcggaatttg gtgtctgata ttcccaatct tgcaaaccat aagatgccac cagctgctgc tgaagagact cctccgtaca gtaattataa cacacttccc tgtaggaaat ctcactgtct ctctgaaggt gccaccaacc cacaaattag ccatagcaac agcatgcaag gcagaagagc taaaacaact caggatgtta atgcaggcga gggcagtgag tttgcagaca gtgggattga aggggccact accgacacgg acctcctgtc caggcgatct aatgccacca actccagcta ctcacccacc acaggccggg cctttgtggg cagcgacagc ggcagcagct ccaccgggga tgcggctcgt cagggggtgt acgagaactt ccggcgggag ctggagatga gcaccaccaa cagcgagagc ctggaggagg ccggctcggc gcacagcgat gagcagagca gcggcaccct gagctctccg ggccagtcgg acatcctgct gaccgccgca cagggcacgg tgcgcaaggc cggcgccctg gccgtcaaga acttcctggt gcacaagaag aacaagaagg tggagtcagc cacccggagg aagtggaagc actactgggt gtccctgaaa ggatgcacgc tatttttcta cgagagcgac ggcaggtctg ggatagacca caacagcatc cccaaacacg ccgtctgggt ggagaacagc attgtgcagg cggtgcctga gcaccccaag aaggactttg tcttctgcct cagcaattcc ctgggtgatg ccttcctttt tcagaccact agccagacgg agcttgaaaa ctggatcacc gccatccact ctgcctgcgc cactgcggtc gcgaggcacc accacaagga agacacgctc cgactcctga aatcagagat caaaaaactg gaacagaaga ttgacatgga tgaaaagatg aagaaaatgg gtgaaatgca gctgtcttca gtcactgact caaagaaaaa gaaaacaata ttagatcaga tctttgtctg ggagcaaaat ctcgagcagt tccaaatgga cctgtttcgt ttccgctgtt atttagccag ccttcagggt ggggagctgc caaaccccaa aaggcttctc gcttttgcaa gtcgaccaac gaaagtggcc atgggccgcc ttggaatctt ttcggtatca tcgtttcatg ccctggtggc agcacgcact ggtgaaactg gagtgagaag acgtactcag gccatgtcca gatccgcgag caagcgaagg agcaggtttt cttctctgtg gggtctggat actacctcca aaaagaagca gggacggcca agcatcaatc aggtgtttgg agagggaacc gaagctgtaa agaaatcttt agagggaata tttgatgaca ttgttccaga tggcaagagg gagaaagaag tggtcttacc taacgttcac cagcacaacc ctgactgcga catttgggtc cacgagtatt tcactccatc ctggttctgt ctgcccaata atcagcctgc cctgacggtc gtccggccag gcgacactgc acgggacacc ctggagctga tttgcaagac acatcaactg gatcattctg ctcattacct gcgcctgaaa tttctaatag aaaacaaaat gcagctctat gttccacagc ccgaggaaga catctatgag ctgctgtaca aagaaattga aatctgtcca aaagtcactc agagcatcca cattgagaag tcagatacag ctgctgatac ttacgggttt tcactttctt ctgtggaaga agatggtatt cgaaggctgt acgtgaatag tgtgaaggaa accggtttag cttccaagaa aggcctgaaa gcaggagatg agattcttga gatcaataat cgtgctgctg acgccctgaa ctcttctatg ctcaaagatt tcctctcaca gccctcgctg ggcctcctgg tgaggaccta ccccgagctg gaggaaggag tggagctgct ggaaagcccg ccccaccgag tggacggccc tgccgacctt ggcgagagcc ccctcgcctt tctcaccagc aacccagggc acagcctttg cagcgagcag ggcagcagtg ctgagaccgc tccagaggag accgaggggc cagacttgga atcctcagat gagactgatc acagcagcaa gagtacagaa caggtggccg cattttgccg cagtttgcat gagatgaacc cctctgacca gagcccatct cctcaggact ccacggggcc tcagctggcg accatgagac aactctcgga tgcagataag ctgcgcaagg tgatctgcga gctcctggag acggagcgca cctacgtgaa ggatttaaac tgtcttatgg agagatacct aaagcctctt caaaaagaaa cttttctcac ccaggatgag cttgacgtgc tttttggaaa tttaacggaa atggtagagt ttcaagtaga attccttaaa actctagaag atggagtgag actggtacct gatttggaaa agcttgagaa ggttgatcaa tttaagaaag tgctgttctc tctgggggga tcattcctgt attatgctga ccgcttcaag ctctacagtg ccttctgcgc cagccacaca aaagttccca aggtcctggt gaaagccaag acagacacgg ctttcaaggc attcttggat gcccagaacc cgaagcagca gcactcatcc acgctggagt cgtacctcat caagcccatc cagaggatcc tcaagtaccc acttctgctc agggagctgt tcgccctgac cgatgcggag agcgaggagc actaccacct ggacgtggcc atcaagacca tgaacaaggt tgccagtcac atcaatgaga tgcagaaaat ccatgaagag tttggggctg tgtttgacca gctgattgct gaacagactg gtgagaaaaa agaggttgca gatctgagca tgggagacct gcttttgcac actaccgtga tctggctgaa cccgccggcc tcgctgggca agtggaaaaa ggaaccagag ttggcagcat tcgtcttcaa aactgctgtg gtccttgtgt ataaagatgg ttccaaacag aagaagaaac ttgtaggatc tcacaggctt tccatttatg aggactggga ccccttcaga tttcgacaca tgatccccac ggaagcgctg caggttcgag ctttggcgag tgcagatgca gaggcaaatg ccgtgtgtga aattgtccat gtaaaatccg agtctgaagg gaggccggag agggtctttc acttgtgctg cagctcccca gagagccgaa aggatttcct aaaggctgtg cattcaatcc tgcgtgataa gcacagaaga cagctcctca aaaccgagag ccttccctca tcccagcaat atgtcccttt tggaggcaaa agattgtgtg cactgaaggg ggccaggccg gccatgagca gggcagtgtc tgccccaagc aagtctcttg ggaggaggag gcggcggctg gctcgaaaca ggtttaccat tgattctgat gccgtctccg caagcagccc ggagaaagag tcccagcagc cccccggtgg tggggacact gaccgatggg tagaggagca gtttgatctt gctcagtatg aggagcaaga tgacatcaag gagacagaca tcctcagtga cgatgatgag ttctgtgagt ccgtgaaggg tgcctcagtg gacagagacc tgcaggagcg gcttcaggcc acctccatca gtcagcggga aagaggccgg aaaaccctgg atagtcacgc gtcccgcatg gcacagctca agaagcaagc tgccctgtcg gggatcaatg gaggcctgga gagcgcaagc gaggaagtca tttgggttag gcgtgaagac tttgccccct ccaggaaact gaacactgag atctga. It is sometimes possible for the material contained within the vial of "TIAM1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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