RPH3AL cdna clone
RPH3AL cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]
Uniprot Description
RPH3AL: Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: cytoplasm; plasma membrane
Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; cytoskeletal protein binding; protein binding; syntaxin binding
Biological Process: calcium ion-dependent exocytosis of neurotransmitter; exocytosis; regulation of calcium ion-dependent exocytosis; vesicle fusion
Research Articles on RPH3AL
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Product Notes
The RPH3AL rph3al (Catalog #AAA1266873) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCCGACA CCATCTTCGG CAGCGGGAAT GATCAGTGGG TTTGCCCCAA TGACCGGCAG CTTGCCCTTC GAGCCAAGCT GCAGACGGGC TGGTCCGTGC ACACCTACCA GACGGAGAAG CAGAGGAGGA AGCAGCACCT CAGCCCGGCG GAGGTGGAGG CCATCCTGCA GGTCATCCAG AGGGCAGAGC GGCTCGACGT CCTGGAGCAG CAGAGAATCG GGCGGCTGGT GGAGCGGCTG GAGACCATGA GGCGGAATGT GATGGGGAAC GGCCTGTCCC AGTGTCTGCT CTGCGGGGAG GTGCTGGGCT TCCTGGGCAG CTCGTCGGTG TTCTGCAAAG ACTGCAGGAA GAAAGTCTGC ACCAAATGTG GGATCGAGGC CTCCCCTGGC CAGAAGCGGC CCCTGTGGCT GTGTAAGATC TGCAGTGAGC AAAGAGAGGT CTGGAAGAGG TCGGGGGCCT GGTTCTACAA AGGGCTCCCC AAGTATATCT TGCCCCTGAA GACCCCTGGC CGAGCTGATG ACCCCCACTT CCGACCTTTG CCCACGGAAC CGGCAGAGCG AGAGCCCAGA AGCTCTGAGA CCAGCCGCAT CTACACGTGG GCCCGAGGAA GAGTGGTTTC CAGTGACAGT GACAGTGACT CGGATCTTAG CTCCTCCAGC CTAGAGGACA GACTCCCATC CACTGGGGTC AGGGACCGGA AAGGCGACAA ACCCTGGAAG GAGTCAGGTG GCAGCGTGGA GGCCCCCAGG ATGGGGTTCA CCCACCCGCC GGGCCACCTC TCTGGGTGCC AGAGCAGCCT GGCCAGTGGT GAGACGGGGA CAGGCTCTGC TGACCCGCCA GGGGGACCCC GCCCCGGGCT GACCCGAAGG GCCCCGGTAA AAGACACACC TGGACGAGCC CCCGCTGCTG ACGCAGCTCC AGCAGGCCCC TCCAGCTGCC TGGGCTGA. It is sometimes possible for the material contained within the vial of "RPH3AL, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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