Rabbit UQCRQ Polyclonal Antibody | anti-UQCRQ antibody

UQCRQ Antibody

Cat. Num. AAA9603724

• Gene Names: UQCRQ; QPC; QCR8; QP-C; UQCR7; MC3DN4
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: UQCRQ; Polyclonal Antibody; UQCRQ Antibody; Complex III subunit 8; Complex III subunit VIII; Cytochrome b-c1 complex subunit 8; QCR8; QCR8_HUMAN; QP-C; QPC; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; Uqcrq; anti-UQCRQ antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: UQCRQ antibody detects endogenous levels of UQCRQ.
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 82

• Applicable Applications for anti-UQCRQ antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: A synthesized peptide derived from human UQCRQ.
• Subcellular Location: Mitochondrion Inner Membrane.
• Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
• Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Immunohistochemistry (IHC)

(MBS9603724 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

Western Blot (WB)

(Western blot analysis of extracts of HepG2 cells, using UQCRQ antibody.)

Related Product Information for anti-UQCRQ antibody

Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
Subunit Structure: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
Similarity: Belongs to the UQCRQ/QCR8 family.

NCBI and Uniprot Product Information

• NCBI GI #: 83367083
• NCBI GeneID: 27089
• NCBI Accession #: NP_055217.2
• NCBI GenBank Nucleotide #: NM_014402.4
• UniProt Accession #: O14949; Q5FVE2; Q9BV88; Q9T2V7
• Molecular Weight: Observed: 10 kDa; Predicted: 10 kDa
• NCBI Official Full Name: cytochrome b-c1 complex subunit 8
• NCBI Official Synonym Full Names: ubiquinol-cytochrome c reductase complex III subunit VII
• NCBI Official Symbol: UQCRQ
• NCBI Official Synonym Symbols: QPC; QCR8; QP-C; UQCR7; MC3DN4
• NCBI Protein Information: cytochrome b-c1 complex subunit 8
• UniProt Protein Name: Cytochrome b-c1 complex subunit 8
• UniProt Gene Name: UQCRQ

NCBI Description

This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]

Uniprot Description

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.