RGS5 cdna clone
RGS5 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]
Uniprot Description
RGS5: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, RGS; GAPs
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: cytoplasm; plasma membrane
Molecular Function: GTPase activator activity
Biological Process: regulation of G-protein coupled receptor protein signaling pathway
Disease: Hypertension, Essential
Research Articles on RGS5
Similar Products
Product Notes
The RGS5 rgs5 (Catalog #AAA1276409) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtgcaaag gacttgcagc tttgccccac tcatgcctgg aaagggccaa ggagattaag atcaagttgg gaattctcct ccagaagcca gactcagttg gtgaccttgt cattccgtac aatgagaagc cagagaaacc agccaagacc cagaaaacct cgctggacga ggccctgcag tggcgtgatt ccctggacaa actcctgcag aacaactatg gacttgccag tttcaaaagt ttcctgaagt ctgaattcag tgaggaaaac cttgagttct ggattgcctg tgaggattac aagaagatca agtcccctgc caagatggct gagaaggcaa agcaaattta tgaagaattc attcaaacgg aggctcctaa agaggtgaat attgaccact tcactaagga catcacaatg aagaacctgg tggaaccttc cctgagcagc tttgacatgg cccagaaaag aatccatgcc ctgatggaaa aggattctct gcctcgcttt gtgcgctctg agttttatca ggagttaatc aagtag. It is sometimes possible for the material contained within the vial of "RGS5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
