RDBP cdna clone
RDBP cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]
Uniprot Description
RDBP: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Belongs to the RRM NELF-E family.
Protein type: Transcription, coactivator/corepressor; Mitochondrial
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: nucleoplasm
Molecular Function: protein binding
Biological Process: positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on RDBP
Similar Products
Product Notes
The RDBP nelfe (Catalog #AAA1276909) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgttggtga taccccccgg actgagcgag gaagaggagg ctctgcagaa gaaattcaac aagctcaaga aaaagaaaaa ggcattgctg gctctgaaga agcaaagtag cagcagcaca accagccaag gtggtgtcaa acgctcacta tcagagcagc ctgtcatgga cacagccaca gcaacagagc aggcaaagca gctggtgaag tcaggagcca tcagtgccat caaggctgag accaagaact caggcttcaa gcgttctcga acccttgagg ggaagttaaa ggaccccgag aagggaccag tccccacttt ccagccgttc cagaggagca tatctgctga tgatgacctg caagagtcat ccagacgtcc ccagaggaaa tctctgtatg agagctttgt gtcttctagt gatcgacttc gagaactagg accagatgga gaagaggcag agggcccagg ggctggtgat ggtccccctc gaagctttga ctggggctat gaagaacgca gtggtgccca ctcctcagcc tcccctcccc gaagccgcag ccgggaccgc agccatgaga ggaaccggga cagagaccga gatcgggagc gggatcgaga ccgggatcga gacagagaca gagagcggga cagggatcgg gatcgggatc gagatcgaga ccgggaacgg gacagggatc gggagcggga tcgagaccga gaccgagagg gtcctttccg caggtcggat tcattccctg aacggcgagc ccctaggaaa gggaatactc tctatgtata tggagaagac atgacaccca cccttctccg tggggccttc tctccttttg gaaacatcat tgacctctcc atggacccac ccagaaactg tgccttcgtc acctatgaaa agatggagtc agcagatcag gccgttgctg agctcaacgg gacccaggtg gagtctgtac agctcaaagt caacatagcc cgaaaacagc ccatgctgga tgccgctact ggcaagtctg tctggggctc cctcgctgtc cagaacagcc ctaagggttg ccaccgggac aagaggaccc agattgtcta cagtgatgac gtctacaagg aaaaccttgt ggatggcttc tag. It is sometimes possible for the material contained within the vial of "RDBP, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
