NDUFA2 cdna clone
NDUFA2
Translation Sequence: MAAAAASRGV GAKLGLREIR IHLCQRSPGS QGVRDFIEKR YVELKKANPD LPILIRECSD VQPKLWARYA FGQETNVPLN NFSADQVTRA LENVLSGKA
NCBI and Uniprot Product Information
NCBI Description
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Uniprot Description
NDUFA2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Protein type: EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; Oxidoreductase; Mitochondrial
Chromosomal Location of Human Ortholog: 5q31.2
Cellular Component: mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I
Molecular Function: NADH dehydrogenase (ubiquinone) activity
Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
Disease: Leigh Syndrome
Research Articles on NDUFA2
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Product Notes
The NDUFA2 ndufa2 (Catalog #AAA200799) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGCGGCGG CCGCAGCAAG TCGAGGAGTC GGGGCAAAGC TGGGCCTGCG TGAGATTCGC ATCCACTTAT GTCAGCGCTC GCCCGGCAGC CAGGGCGTCA GGGACTTCAT TGAGAAACGC TACGTGGAGC TGAAGAAGGC GAATCCCGAC CTACCCATCC TAATCCGCGA ATGCTCCGAT GTGCAGCCCA AGCTCTGGGC CCGCTACGCA TTTGGCCAAG AGACGAATGT CCCTTTGAAC AACTTCAGTG CTGATCAGGT AACCAGAGCC CTGGAGAACG TTCTAAGTGG TAAAGCCTGA Tr anslation Sequence: MAAAAASRGV GAKLGLREIR IHLCQRSPGS QGVRDFIEKR YVELKKANPD LPILIRECSD VQPKLWARYA FGQETNVPLN NFSADQVTRA LENVLSGKA. It is sometimes possible for the material contained within the vial of "NDUFA2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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