MYLK3 cdna clone
MYLK3 cDNA Clone
Gene Names
MYLK3; MLCK; MLCK2; caMLCK
Synonyms
MYLK3; MYLK3 cDNA Clone; MYLK3 cdna clone
Sequence
ATGGACACAAAGCTGAACATGCTGAACGAGAAGGTGGACCAGCTCCTGCACTTCCAAGAAGATGTCACAGAGAAGTTGCAGAGCATGTGCCGAGACATGGGCCACCTGGAGCGGGGCCTGCACAGGCTGGAGGCCTCCCGGGCACCGGGCCCGGGCGGGGCTGATGGGGTTCCCCACATTGACACCCAGGCTGGGTGGCCCGAGGTCCTGGAGCTGGTGAGGGCCATGCAGCAGGATGCGGCCCAGCACGGTGCCAGGCTGGAGGCCCTCTTCAGGATGGTGGCTGCGGTGGACAGGGCCATCGCTTTGGTGGGGGCCACGTTCCAGAAATCAAAGGTGGCGGATTTCCTCATGCAGGGGCGTGTGCCCTGGAGGAGAGGCAGCCCAGGTGACAGCCCTGAGGAGAATAAAGAGCGAGTGGAAGAAGAGGGAGGAAAACCAAAGCATGTGCTGAGCACCAGTGGGTTGCAGTCTGATGCCAGGGAGCCTGGGGAAGAGAGCCAGAAGGCGGACGTGCTGGAGGGGACAGCGGAGAGGCTGCCCCCCATCAGAGCGTCAGGGCTGGGAGCTGACCCCGCCCAGGCAGTGGTCTCACCGGGCCAGGGAGATGGTGTTCCTGGCCCAGCCCAGGCATTCCCTGGCCACCTGCCCCTGCCCACAAAGGTGGAAGCCAAGGCTCCTGAGACACCCAGCGAGAACCTCAGGACTGGCCTGGAATTGGCTCCAGCACCCGGCAGGGTCAATGTGGTCTCCCCGAGCCTGGAGGTTGCACCAGGTGCAGGACAAGGAGCATCGTCCAGCAGGCCTGACCCTGAGCCCTTAGAGGAAGGCACGAGGCTGACTCCAGGGCCTGGCCCTCAGTGCCCAGGGCCTCCAGGGCTGCCAGCCCAGGCCAGGGCAACCCACAGTGGTGGAGAAACACCTCCAAGGATCTCCATCCACATACAAGAGATGGATACTCCTGGGGAGATGCTGATGACAGGCAGGGGCAGCCTTGGACCCACCCTCACCACAGAGGCTCCAGCAGCTGCCCAGCCAGGCAAGCAGGGCCCACCTGGGACCGGGCGCTGCCTCCAAGCCCCTGGGACTGAGCCCGGAGAACAGACCCCTGAAGGAGCCAGAGAGCTCTCCCCGCTGCAGGAGAGCAGCAGCCCCGGGGGAGTGAAGGCAGAGGAGGAGCAAAGGGCTGGGGCCGAGCCTGGCACGAGACCAAGCTTGGCCAGGAGTGACGACAATGACCACGAGGTTGGGGCCCTGGGCCTGCAGCAGGGCAAAAGCCCAGGGGCGGGAAACCCTGAGCCTGAGCAGGACTGTGCAGCCAGGGCTCCGGTGAGAGCTGAAGCAGTAAGGAGGATGCCCCCAGGCGCCGAGGCTGGCAGCGTGGTTCTGGATGACAGTCCGGCCCCACCAGCTCCTTTTGAACACCGGGTAGTGAGCGTCAAGGAGACCTCCATCTCTGCGGGTTACGAGGTGTGCCAGCACGAAGTCTTGGGAGGGGGTCGGTTTGGCCAGGTCCACAGGTGCACAGAGAAGTCCACAGGCCTCCCACTGGCTGCCAAGATCATCAAAGTGAAGAGCGCCAAGGACCGGGAGGACGTGAAGAACGAGATCAACATCATGAACCAGCTCAGCCACGTGAACCTGATCCAGCTCTATGACGCCTTCGAGAGCAAGCACAGCTGCACCCTTGTCATGGAGTACGTGGACGGGGGTGAGCTCTTCGACCGGATCACAGATGAGAAGTACCACCTGACTGAGCTGGATGTGGTCCTGTTCACCAGGCAGATCTGTGAGGGTGTGCATTACCTGCACCAGCACTACATCCTGCACCTGGACCTCAAGCCGGAGAACATATTGTGCGTCAATCAGACAGGACATCAAATTAAGATCATTGACTTTGGGCTGGCCAGAAGGTACAAGCCTCGAGAGAAGCTGAAGGTGAACTTCGGCACTCCTGAGTTCCTGGCCCCAGAAGTCGTCAATTATGAGTTTGTCTCATTCCCCACAGACATGTGGAGTGTGGGAGTCATCACCTACATGCTACTCAGTGGCTTGTCCCCATTTCTAGGGGAAACAGATGCAGAGACCATGAATTTCATTGTAAACTGTAGCTGGGATTTTGATGCTGACACCTTTGAAGGGCTCTCGGAGGAGGCCAAGGACTTTGTTTCCCGGTTGCTGGTCAAAGAGAAGAGCTGCAGAATGAGTGCCACACAGTGCCTGAAACACGAGTGGCTGAATAATTTGCCTGCCAAAGCTTCAAGATCCAAAACTCGTCTCAAATCCCAACTACTGCTGCAGAAATACATAGCTCAAAGAAAATGGAAGAAACATTTCTATGTGGTGACTGCTGCCAACAGGTTAAGGAAATTTCCAACTTCTCCCTAA
Sequence Length
2388
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
52,723 Da
NCBI Official Full Name
Homo sapiens myosin light chain kinase 3, mRNA
NCBI Official Synonym Full Names
myosin light chain kinase 3
NCBI Official Symbol
MYLK3
NCBI Official Synonym Symbols
MLCK; MLCK2; caMLCK
NCBI Protein Information
myosin light chain kinase 3
UniProt Protein Name
Myosin light chain kinase 3
Protein Family
UniProt Gene Name
MYLK3
UniProt Synonym Gene Names
MLCK; Cardiac-MLCK
UniProt Entry Name
MYLK3_HUMAN
NCBI Description
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]
Uniprot Description
caMLCK: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, CAMK; EC 2.7.11.18; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CAMK group; MLCK family
Chromosomal Location of Human Ortholog: 16q11.2
Cellular Component: cytoplasm; cytosol
Molecular Function: calmodulin-dependent protein kinase activity; myosin light chain kinase activity
Biological Process: cardiac myofibril assembly; protein amino acid phosphorylation; regulation of vascular permeability during acute inflammatory response; sarcomere organization; sarcomerogenesis
Research Articles on MYLK3
Similar Products
Product Notes
The MYLK3 mylk3 (Catalog #AAA1268827) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGACACAA AGCTGAACAT GCTGAACGAG AAGGTGGACC AGCTCCTGCA CTTCCAAGAA GATGTCACAG AGAAGTTGCA GAGCATGTGC CGAGACATGG GCCACCTGGA GCGGGGCCTG CACAGGCTGG AGGCCTCCCG GGCACCGGGC CCGGGCGGGG CTGATGGGGT TCCCCACATT GACACCCAGG CTGGGTGGCC CGAGGTCCTG GAGCTGGTGA GGGCCATGCA GCAGGATGCG GCCCAGCACG GTGCCAGGCT GGAGGCCCTC TTCAGGATGG TGGCTGCGGT GGACAGGGCC ATCGCTTTGG TGGGGGCCAC GTTCCAGAAA TCAAAGGTGG CGGATTTCCT CATGCAGGGG CGTGTGCCCT GGAGGAGAGG CAGCCCAGGT GACAGCCCTG AGGAGAATAA AGAGCGAGTG GAAGAAGAGG GAGGAAAACC AAAGCATGTG CTGAGCACCA GTGGGTTGCA GTCTGATGCC AGGGAGCCTG GGGAAGAGAG CCAGAAGGCG GACGTGCTGG AGGGGACAGC GGAGAGGCTG CCCCCCATCA GAGCGTCAGG GCTGGGAGCT GACCCCGCCC AGGCAGTGGT CTCACCGGGC CAGGGAGATG GTGTTCCTGG CCCAGCCCAG GCATTCCCTG GCCACCTGCC CCTGCCCACA AAGGTGGAAG CCAAGGCTCC TGAGACACCC AGCGAGAACC TCAGGACTGG CCTGGAATTG GCTCCAGCAC CCGGCAGGGT CAATGTGGTC TCCCCGAGCC TGGAGGTTGC ACCAGGTGCA GGACAAGGAG CATCGTCCAG CAGGCCTGAC CCTGAGCCCT TAGAGGAAGG CACGAGGCTG ACTCCAGGGC CTGGCCCTCA GTGCCCAGGG CCTCCAGGGC TGCCAGCCCA GGCCAGGGCA ACCCACAGTG GTGGAGAAAC ACCTCCAAGG ATCTCCATCC ACATACAAGA GATGGATACT CCTGGGGAGA TGCTGATGAC AGGCAGGGGC AGCCTTGGAC CCACCCTCAC CACAGAGGCT CCAGCAGCTG CCCAGCCAGG CAAGCAGGGC CCACCTGGGA CCGGGCGCTG CCTCCAAGCC CCTGGGACTG AGCCCGGAGA ACAGACCCCT GAAGGAGCCA GAGAGCTCTC CCCGCTGCAG GAGAGCAGCA GCCCCGGGGG AGTGAAGGCA GAGGAGGAGC AAAGGGCTGG GGCCGAGCCT GGCACGAGAC CAAGCTTGGC CAGGAGTGAC GACAATGACC ACGAGGTTGG GGCCCTGGGC CTGCAGCAGG GCAAAAGCCC AGGGGCGGGA AACCCTGAGC CTGAGCAGGA CTGTGCAGCC AGGGCTCCGG TGAGAGCTGA AGCAGTAAGG AGGATGCCCC CAGGCGCCGA GGCTGGCAGC GTGGTTCTGG ATGACAGTCC GGCCCCACCA GCTCCTTTTG AACACCGGGT AGTGAGCGTC AAGGAGACCT CCATCTCTGC GGGTTACGAG GTGTGCCAGC ACGAAGTCTT GGGAGGGGGT CGGTTTGGCC AGGTCCACAG GTGCACAGAG AAGTCCACAG GCCTCCCACT GGCTGCCAAG ATCATCAAAG TGAAGAGCGC CAAGGACCGG GAGGACGTGA AGAACGAGAT CAACATCATG AACCAGCTCA GCCACGTGAA CCTGATCCAG CTCTATGACG CCTTCGAGAG CAAGCACAGC TGCACCCTTG TCATGGAGTA CGTGGACGGG GGTGAGCTCT TCGACCGGAT CACAGATGAG AAGTACCACC TGACTGAGCT GGATGTGGTC CTGTTCACCA GGCAGATCTG TGAGGGTGTG CATTACCTGC ACCAGCACTA CATCCTGCAC CTGGACCTCA AGCCGGAGAA CATATTGTGC GTCAATCAGA CAGGACATCA AATTAAGATC ATTGACTTTG GGCTGGCCAG AAGGTACAAG CCTCGAGAGA AGCTGAAGGT GAACTTCGGC ACTCCTGAGT TCCTGGCCCC AGAAGTCGTC AATTATGAGT TTGTCTCATT CCCCACAGAC ATGTGGAGTG TGGGAGTCAT CACCTACATG CTACTCAGTG GCTTGTCCCC ATTTCTAGGG GAAACAGATG CAGAGACCAT GAATTTCATT GTAAACTGTA GCTGGGATTT TGATGCTGAC ACCTTTGAAG GGCTCTCGGA GGAGGCCAAG GACTTTGTTT CCCGGTTGCT GGTCAAAGAG AAGAGCTGCA GAATGAGTGC CACACAGTGC CTGAAACACG AGTGGCTGAA TAATTTGCCT GCCAAAGCTT CAAGATCCAA AACTCGTCTC AAATCCCAAC TACTGCTGCA GAAATACATA GCTCAAAGAA AATGGAAGAA ACATTTCTAT GTGGTGACTG CTGCCAACAG GTTAAGGAAA TTTCCAACTT CTCCCTAA. It is sometimes possible for the material contained within the vial of "MYLK3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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