MTIF3 cdna clone
MTIF3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009]
Uniprot Description
MTIF3: IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. Belongs to the IF-3 family.
Protein type: Mitochondrial; Translation; Translation initiation
Chromosomal Location of Human Ortholog: 13q12.2
Cellular Component: mitochondrion
Molecular Function: protein binding; ribosomal small subunit binding; ribosome binding; translation factor activity, nucleic acid binding; translation initiation factor activity
Biological Process: ribosome disassembly
Research Articles on MTIF3
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Product Notes
The MTIF3 mtif3 (Catalog #AAA1267842) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctgctc tttttctaaa gaggttaaca ctacaaactg taaagtctga aaatagttgc attagatgtt ttggtaaaca catcctgcaa aagacagcac cagcacagtt gtcccctatt gcttctgccc caagactctc cttcctaatt catgcaaaag cctttagtac cgctgaagac acccagaatg aaggaaaaaa gataaaaaag aataaaacag cttttagtaa cgttggaaga aaaattagtc agcgagttat tcacttattt gatgagaagg gcaatgattt gggaaacatg caccgagcaa atgtgattag acttatggat gagcgagacc tgcgactggt tcaaaggaac accagcacag aacctgcaga gtatcagctc atgacaggat tgcagatcct ccaggagcgg cagaggctga gggagatgga gaaggcgaac cccaaaactg gaccaaccct gagaaaggaa ctgattttgt cttcaaatat tggacaacat gatttggaca caaagactaa acagattcag cagtggatta agaaaaaaca cctagtccag attaccataa agaaaggaaa aaatgtagac gtgtcagaaa atgaaatgga ggagatattt catcaaatac tccagactat gcctggaata gctacattct catctaggcc acaagctgtt caaggaggaa aagctttaat gtgtgttctt cgtgctttga gcaaaaatga ggagaaggca tataaagaaa ctcaagagac ccaggaaaga gacactttga acaaagacca tggaaatgat aaggaatcaa atgttctgca tcagtaa. It is sometimes possible for the material contained within the vial of "MTIF3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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