Rabbit anti-Human MTIF3 Polyclonal Antibody | anti-MTIF3 antibody

MTIF3 Antibody

Cat. Num. AAA7044459

• Gene Names: MTIF3; IF3mt
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: MTIF3; Polyclonal Antibody; MTIF3 Antibody; Translation initiation factor IF-3; mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt; DC38; anti-MTIF3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 278

• Applicable Applications for anti-MTIF3 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC: 1:20-1:200
• Species: Human
• Immunogen: Recombinant human Translation initiation factor IF-3, mitochondrial protein (1-278AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-84313 / sc-84315
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7044459 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7044459 at dilution of 1:100)

Related Product Information for anti-MTIF3 antibody

IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.

NCBI and Uniprot Product Information

• NCBI GI #: 261878554
• NCBI GeneID: 219402
• NCBI Accession #: NP_001159733.1
• NCBI GenBank Nucleotide #: NM_001166261.1
• UniProt Accession #: Q9H2K0; Q05BL8; Q5W0V0; Q86X68
• Molecular Weight: 31,725 Da
• NCBI Official Full Name: translation initiation factor IF-3, mitochondrial
• NCBI Official Synonym Full Names: mitochondrial translational initiation factor 3
• NCBI Official Symbol: MTIF3
• NCBI Official Synonym Symbols: IF3mt
• NCBI Protein Information: translation initiation factor IF-3, mitochondrial
• UniProt Protein Name: Translation initiation factor IF-3, mitochondrial
• UniProt Gene Name: MTIF3
• UniProt Synonym Gene Names: IF-3(Mt); IF-3Mt; IF3(mt); IF3mt
• UniProt Entry Name: IF3M_HUMAN

NCBI Description

This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009]

Uniprot Description

MTIF3: IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. Belongs to the IF-3 family.

Protein type: Translation; Translation initiation; Mitochondrial

Chromosomal Location of Human Ortholog: 13q12.2

Cellular Component: mitochondrion

Molecular Function: protein binding; ribosomal small subunit binding; translation factor activity, nucleic acid binding

Biological Process: ribosome disassembly