KLHL15 cdna clone
KLHL15 cDNA Clone
Gene Names
KLHL15; HEL-S-305
Synonyms
KLHL15; KLHL15 cDNA Clone; KLHL15 cdna clone
Sequence
ATGGCAGGGGACGTGGAAGGATTCTGTTCCTCCATCCACGACACCAGTGTCTCTGCTGGGTTCAGAGCACTGTATGAGGAGGGATTGCTTCTTGATGTCACTCTGGTTATTGAAGATCATCAGTTCCAGGCCCATAAAGCACTCTTGGCCACCCAGAGTGATTACTTCAGAATTATGTTTACTGCAGACATGAGGGAACGAGATCAGGACAAAATTCATTTAAAAGGTCTAACAGCTACCGGTTTCAGCCATGTCCTGCAATTTATGTACTATGGAACTATAGAGCTGAGTATGAATACCGTTCATGAGATTCTTCAGGCTGCCATGTATGTTCAACTTATAGAAGTGGTGAAGTTCTGCTGCTCTTTTCTCTTAGCGAAGATCTGCCTAGAAAATTGTGCAGAAATTATGAGACTCTTAGATGATTTCGGCGTAAACATCGAGGGAGTCAGGGAGAAGTTAGACACCTTTCTGCTAGACAACTTTGTGCCACTCATGTCTAGGCCTGACTTTCTGTCCTATCTGAGCTTTGAGAAGCTCATGTCTTACTTGGATAATGATCATCTGAGCAGGTTCCCAGAGATAGAGCTGTACGAGGCTGTGCAGTCTTGGCTGCGGCATGATAGAAGACGCTGGAGACATACCGATACCATCATTCAGAATATCCGGTTTTGCTTGATGACCCCAACCAGCGTTTTTGAGAAGGTTAAGACATCAGAATTTTATAGATACTCCCGACAGCTCCGTTACGAAGTTGACCAAGCATTGAATTACTTTCAGAATGTTCACCAGCAGCCTTTGTTGGATATGAAGTCAAGCCGCATCCGTTCTGCAAAACCGCAAACTACAGTATTTCGAGGAATGATTGGACATAGCATGGTTAACAGTAAAATACTTCTCTTAAAGAAACCAAGAGTCTGGTGGGAGCTAGAAGGCCCACAAGTACCTCTGCGACCTGACTGCCTTGCTATCGTCAATAATTTTGTGTTCCTGTTAGGCGGGGAAGAGCTGGGCCCGGATGGTGAATTCCATGCTTCTTCCAAAGTATTCAGGTATGACCCGAGACAGAACTCCTGGCTGCAGATGGCAGATATGTCTGTACCACGCTCTGAATTTGCTGTAGGTGTTATTGGGAAGTTTATTTACGCCGTAGCAGGCAGAACCAGAGATGAGACTTTCTATTCAACTGAGAGATATGACATCACCAACGATAAATGGGAATTTGTGGATCCTTATCCAGTTAACAAATATGGACATGAGGGGACAGTGCTCAATAACAAATTGTTTATCACCGGTGGAATCACCTCATCTTCCACCTCCAAGCAAGTGTGCGTGTTTGACCCCAGCAAAGAAGGGACCATAGAACAACGGACCAGGAGAACTCAAGTGGTTACCAACTGTTGGGAGAATAAGAGCAAGATGAATTACGCGAGATGCTTTCACAAGATGATTTCTTACAATGGCAAGCTTTATGTCTTCGGTGGTGTCTGTGTGATCTTGAGGGCCTCTTTCGAATCTCAGGGATGCCCTTCTACAGAAGTATACAACCCAGAGACTGATCAGTGGACCATCTTGGCATCCATGCCGATTGGTAGAAGTGGCCATGGTGTGACTGTGCTGGACAAACAAATAATGGTTCTTGGAGGCCTTTGTTATAATGGTCATTACAGCGATTCCATCCTCACTTTTGATCCGGATGAAAACAAGTGGAAGGAAGATGAGTACCCTCGGATGCCCTGCAAGCTGGATGGTTTACAAGTATGCAACCTGCATTTTCCGGACTATGTACTGGATGAGGTCAGGCGTTGCAACTAA
Sequence Length
1815
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
69,775 Da
NCBI Official Full Name
Homo sapiens kelch-like 15 (Drosophila), mRNA
NCBI Official Synonym Full Names
kelch like family member 15
NCBI Official Symbol
KLHL15
NCBI Official Synonym Symbols
HEL-S-305
NCBI Protein Information
kelch-like protein 15
UniProt Protein Name
Kelch-like protein 15
Protein Family
UniProt Gene Name
KLHL15
UniProt Synonym Gene Names
KIAA1677
UniProt Entry Name
KLH15_HUMAN
NCBI Description
This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009]
Uniprot Description
KLHL15: a substrate-specific adapter for the recruitment of substrates to Cul3-based E3 ubiquitin ligases. KLHL15-Cul3 specifically targets the PP2A regulatory subunit PPP2R5B to promote its turnover by ubiquitylation and proteasomal degradation. May contribute to the selective expression of the PP2A/B holoenzyme in the brain.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: Xp22.1-p21
Molecular Function: ubiquitin-protein ligase activity
Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on KLHL15
Similar Products
Product Notes
The KLHL15 klhl15 (Catalog #AAA1276884) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCAGGGG ACGTGGAAGG ATTCTGTTCC TCCATCCACG ACACCAGTGT CTCTGCTGGG TTCAGAGCAC TGTATGAGGA GGGATTGCTT CTTGATGTCA CTCTGGTTAT TGAAGATCAT CAGTTCCAGG CCCATAAAGC ACTCTTGGCC ACCCAGAGTG ATTACTTCAG AATTATGTTT ACTGCAGACA TGAGGGAACG AGATCAGGAC AAAATTCATT TAAAAGGTCT AACAGCTACC GGTTTCAGCC ATGTCCTGCA ATTTATGTAC TATGGAACTA TAGAGCTGAG TATGAATACC GTTCATGAGA TTCTTCAGGC TGCCATGTAT GTTCAACTTA TAGAAGTGGT GAAGTTCTGC TGCTCTTTTC TCTTAGCGAA GATCTGCCTA GAAAATTGTG CAGAAATTAT GAGACTCTTA GATGATTTCG GCGTAAACAT CGAGGGAGTC AGGGAGAAGT TAGACACCTT TCTGCTAGAC AACTTTGTGC CACTCATGTC TAGGCCTGAC TTTCTGTCCT ATCTGAGCTT TGAGAAGCTC ATGTCTTACT TGGATAATGA TCATCTGAGC AGGTTCCCAG AGATAGAGCT GTACGAGGCT GTGCAGTCTT GGCTGCGGCA TGATAGAAGA CGCTGGAGAC ATACCGATAC CATCATTCAG AATATCCGGT TTTGCTTGAT GACCCCAACC AGCGTTTTTG AGAAGGTTAA GACATCAGAA TTTTATAGAT ACTCCCGACA GCTCCGTTAC GAAGTTGACC AAGCATTGAA TTACTTTCAG AATGTTCACC AGCAGCCTTT GTTGGATATG AAGTCAAGCC GCATCCGTTC TGCAAAACCG CAAACTACAG TATTTCGAGG AATGATTGGA CATAGCATGG TTAACAGTAA AATACTTCTC TTAAAGAAAC CAAGAGTCTG GTGGGAGCTA GAAGGCCCAC AAGTACCTCT GCGACCTGAC TGCCTTGCTA TCGTCAATAA TTTTGTGTTC CTGTTAGGCG GGGAAGAGCT GGGCCCGGAT GGTGAATTCC ATGCTTCTTC CAAAGTATTC AGGTATGACC CGAGACAGAA CTCCTGGCTG CAGATGGCAG ATATGTCTGT ACCACGCTCT GAATTTGCTG TAGGTGTTAT TGGGAAGTTT ATTTACGCCG TAGCAGGCAG AACCAGAGAT GAGACTTTCT ATTCAACTGA GAGATATGAC ATCACCAACG ATAAATGGGA ATTTGTGGAT CCTTATCCAG TTAACAAATA TGGACATGAG GGGACAGTGC TCAATAACAA ATTGTTTATC ACCGGTGGAA TCACCTCATC TTCCACCTCC AAGCAAGTGT GCGTGTTTGA CCCCAGCAAA GAAGGGACCA TAGAACAACG GACCAGGAGA ACTCAAGTGG TTACCAACTG TTGGGAGAAT AAGAGCAAGA TGAATTACGC GAGATGCTTT CACAAGATGA TTTCTTACAA TGGCAAGCTT TATGTCTTCG GTGGTGTCTG TGTGATCTTG AGGGCCTCTT TCGAATCTCA GGGATGCCCT TCTACAGAAG TATACAACCC AGAGACTGAT CAGTGGACCA TCTTGGCATC CATGCCGATT GGTAGAAGTG GCCATGGTGT GACTGTGCTG GACAAACAAA TAATGGTTCT TGGAGGCCTT TGTTATAATG GTCATTACAG CGATTCCATC CTCACTTTTG ATCCGGATGA AAACAAGTGG AAGGAAGATG AGTACCCTCG GATGCCCTGC AAGCTGGATG GTTTACAAGT ATGCAACCTG CATTTTCCGG ACTATGTACT GGATGAGGTC AGGCGTTGCA ACTAA. It is sometimes possible for the material contained within the vial of "KLHL15, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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