IQSEC1 cdna clone

IQSEC1 cDNA Clone

Gene Names

IQSEC1; BRAG2; GEP100; ARFGEP100; ARF-GEP100

Synonyms

IQSEC1; IQSEC1 cDNA Clone; IQSEC1 cdna clone

Ordering
Cat. Num. AAA1275146 For Research Use Only!

Sequence

atgctagaacgaaagtatggggggcgcctggtaacccgccatgcggcccgcaccatccagacggcgtttcgccagtaccagatgaacaagaacttcgagcgcttgcgcagctccatgtcagagaaccgcatgtcacgccggattgtgctgtccaacatgaggatgcagttctcctttgaggggcctgagaaagtgcacagctcctacttcgaggggaagcaggtctcagtgactaacgacggctcccagctgggagccctggtgtcccctgagtgtggtgacctcagcgagcccaccaccctcaagtctccggccccctccagtgactttgcggacgccatcaccgagctggaggacgccttctctaggcaagtgaaatcactggccgagtccatcgacgatgccctcaactgccgcagcctgcacactgaggaggcaccggccctggatgcggcgcgggcccgggacaccgaaccccagacagccctgcacggcatggaccaccgcaaactggacgagatgacggcctcgtacagtgatgtcaccctgtacatcgatgaggaggagctgtcgccccctctgcccctctcgcaggcaggggaccggccgtccagcaccgagtcggacctgcggctacgggctgggggcgcagccccagactactgggccctggcccacaaagaggacaaggctgacacggacacgagctgccggagcacgccgtcgctggagcggcaggagcagcggctgcgggtggagcatctgccgctgctcaccatcgagccacccagcgacagctctgtggaccttagtgaccgctcggagcgggggtcactcaagaggcagagtgcttacgagcgcagccttggcgggcagcagggcagtcccaagcatggtccccacagcggcgcccccaagagcctcccccgggaggagcctgagttgcggccccggccccccaggcccctggacagccacttggccatcaatggctcagccaaccggcagagcaagtctgagtcggactactcagacggtgacaatgacagcatcaacagcacgtccaactccaacgataccatcaactgcagctccgagtcatcgtcccgtgacagcctgcgggagcagacgctcagcaagcagacctaccacaaggaggcccgcaacagctgggactcgcctgcctttagcaacgatgtcatccgcaagaggcactaccgcatcggcctgaacctcttcaacaagaagcctgagaagggagtccagtacctcatcgagcgtggctttgtgcccgacacgcccgtcggggtggcccacttcctgctgcagcgcaagggcctcagccggcagatgatcggcgagttcctgggcaaccggcagaagcagttcaaccgtgacgtgctcgactgcgtcgtggacgagatggacttctctaccatggagctggatgaggccctcaggaaattccaggcgcacatccgtgtccaaggggaggctcagaaagtggagcggctcatagaggcgttcagccagcgctactgcatctgcaaccctggggtggtgcggcaattccggaacccagacaccattttcatcctggccttcgccatcatcctgctgaacaccgacatgtacagccccaatgtcaagcccgagcggaaaatgaagctagaggacttcatcaagaacctccgaggtgtggacgatggtgaggacattccccgtgagatgctgatggggatctatgaacggatccgtaagcgagagctaaagaccaatgaggaccatgtgtcccaggtgcagaaggtggagaagctcattgtggggaaaaagccgatcggatccctgcatcccgggctcggctgtgtgctctctctgccccaccgtcggttggtctgctactgccggctctttgaggttccagacccaaacaagccccagaaactcggactacaccagcgagaaatcttcctgttcaacgacctcctggtggtcaccaagatcttccagaagaagaagaactcggtgacgtacagcttccgacagtccttctccttgtacggcatgcaggtcctgctcttcgagaaccagtactaccccaatggcatccggctcacctcgtctgtccccggagcagatatcaaagtgttaataaacttcaacgcccccaaccctcaagaccggaagaaattcaccgatgacctgcgggagtccattgcggaagtccaagagatggagaagcacaggatagagtcggagctcgagaagcagaaaggcgtcgtgcggcccagcatgtcccagtgctctagcctcaaaaaggagtcgggcaacggaacactgagccgggcctgcctggacgacagctatgccagcggtgagggcctcaagcgcagcgccctcagcagctccctgcgggacctctcggaagccggggtccatcattag

Sequence Length

2445

Vector

Please Inquire

NCBI and Uniprot Product Information

NCBI GI #

16307438

NCBI GeneID

9922

Molecular Weight

94,914 Da

NCBI Official Full Name

Homo sapiens IQ motif and Sec7 domain 1, mRNA

NCBI Official Synonym Full Names

IQ motif and Sec7 domain 1

NCBI Official Symbol

IQSEC1

NCBI Official Synonym Symbols

BRAG2; GEP100; ARFGEP100; ARF-GEP100

NCBI Protein Information

IQ motif and SEC7 domain-containing protein 1

UniProt Protein Name

IQ motif and SEC7 domain-containing protein 1

Protein Family

IQ motif and SEC7 domain-containing protein

UniProt Gene Name

IQSEC1

UniProt Synonym Gene Names

ARFGEP100; BRAG2; KIAA0763; BRAG2

UniProt Entry Name

IQEC1_HUMAN

Uniprot Description

IQSEC1: In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin. Belongs to the BRAG family. Interacts with ARF6. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, ARF; Motility/polarity/chemotaxis; GAPs

Chromosomal Location of Human Ortholog: 3p25.2

Cellular Component: membrane

Biological Process: actin cytoskeleton organization and biogenesis

Research Articles on IQSEC1

1. Brag2 is essential for developmental and pathological angiogenesis by promoting endothelial cell sprouting through regulation of adhesion by beta1-integrin internalization and link for the first time the process of beta1-integrin endocytosis with angiogenesis.

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Product Notes

The IQSEC1 iqsec1 (Catalog #AAA1275146) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgctagaac gaaagtatgg ggggcgcctg gtaacccgcc atgcggcccg caccatccag acggcgtttc gccagtacca gatgaacaag aacttcgagc gcttgcgcag ctccatgtca gagaaccgca tgtcacgccg gattgtgctg tccaacatga ggatgcagtt ctcctttgag gggcctgaga aagtgcacag ctcctacttc gaggggaagc aggtctcagt gactaacgac ggctcccagc tgggagccct ggtgtcccct gagtgtggtg acctcagcga gcccaccacc ctcaagtctc cggccccctc cagtgacttt gcggacgcca tcaccgagct ggaggacgcc ttctctaggc aagtgaaatc actggccgag tccatcgacg atgccctcaa ctgccgcagc ctgcacactg aggaggcacc ggccctggat gcggcgcggg cccgggacac cgaaccccag acagccctgc acggcatgga ccaccgcaaa ctggacgaga tgacggcctc gtacagtgat gtcaccctgt acatcgatga ggaggagctg tcgccccctc tgcccctctc gcaggcaggg gaccggccgt ccagcaccga gtcggacctg cggctacggg ctgggggcgc agccccagac tactgggccc tggcccacaa agaggacaag gctgacacgg acacgagctg ccggagcacg ccgtcgctgg agcggcagga gcagcggctg cgggtggagc atctgccgct gctcaccatc gagccaccca gcgacagctc tgtggacctt agtgaccgct cggagcgggg gtcactcaag aggcagagtg cttacgagcg cagccttggc gggcagcagg gcagtcccaa gcatggtccc cacagcggcg cccccaagag cctcccccgg gaggagcctg agttgcggcc ccggcccccc aggcccctgg acagccactt ggccatcaat ggctcagcca accggcagag caagtctgag tcggactact cagacggtga caatgacagc atcaacagca cgtccaactc caacgatacc atcaactgca gctccgagtc atcgtcccgt gacagcctgc gggagcagac gctcagcaag cagacctacc acaaggaggc ccgcaacagc tgggactcgc ctgcctttag caacgatgtc atccgcaaga ggcactaccg catcggcctg aacctcttca acaagaagcc tgagaaggga gtccagtacc tcatcgagcg tggctttgtg cccgacacgc ccgtcggggt ggcccacttc ctgctgcagc gcaagggcct cagccggcag atgatcggcg agttcctggg caaccggcag aagcagttca accgtgacgt gctcgactgc gtcgtggacg agatggactt ctctaccatg gagctggatg aggccctcag gaaattccag gcgcacatcc gtgtccaagg ggaggctcag aaagtggagc ggctcataga ggcgttcagc cagcgctact gcatctgcaa ccctggggtg gtgcggcaat tccggaaccc agacaccatt ttcatcctgg ccttcgccat catcctgctg aacaccgaca tgtacagccc caatgtcaag cccgagcgga aaatgaagct agaggacttc atcaagaacc tccgaggtgt ggacgatggt gaggacattc cccgtgagat gctgatgggg atctatgaac ggatccgtaa gcgagagcta aagaccaatg aggaccatgt gtcccaggtg cagaaggtgg agaagctcat tgtggggaaa aagccgatcg gatccctgca tcccgggctc ggctgtgtgc tctctctgcc ccaccgtcgg ttggtctgct actgccggct ctttgaggtt ccagacccaa acaagcccca gaaactcgga ctacaccagc gagaaatctt cctgttcaac gacctcctgg tggtcaccaa gatcttccag aagaagaaga actcggtgac gtacagcttc cgacagtcct tctccttgta cggcatgcag gtcctgctct tcgagaacca gtactacccc aatggcatcc ggctcacctc gtctgtcccc ggagcagata tcaaagtgtt aataaacttc aacgccccca accctcaaga ccggaagaaa ttcaccgatg acctgcggga gtccattgcg gaagtccaag agatggagaa gcacaggata gagtcggagc tcgagaagca gaaaggcgtc gtgcggccca gcatgtccca gtgctctagc ctcaaaaagg agtcgggcaa cggaacactg agccgggcct gcctggacga cagctatgcc agcggtgagg gcctcaagcg cagcgccctc agcagctccc tgcgggacct ctcggaagcc ggggtccatc attag. It is sometimes possible for the material contained within the vial of "IQSEC1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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IQSEC1 cdna clone