C6 cdna clone
C6 cDNA Clone
Synonyms
C6; C6 cDNA Clone; C6 cdna clone
Sequence
atggccagacgctctgtcttgtacttcatcctgctgaatgctctgatcaacaagggccaagcctgcttctgtgatcactatgcatggactcagtggaccagctgctcaaaaacttgcaattctggaacccagagcagacacagacaaatagtagtagataagtactaccaggaaaacttttgtgaacagatttgcagcaagcaggagactagagaatgtaactggcaaagatgccccatcaactgcctcctgggagattttggaccatggtcagactgtgacccttgtattgaaaaacagtctaaagttagatctgtcttgcgtcccagtcagtttgggggacagccatgcactgagcctctggtagcctttcaaccatgcattccatctaagctctgcaaaattgaagaggctgactgcaagaataaatttcgctgtgacagtggccgctgcattgccagaaagttagaatgcaatggagaaaatgactgtggagacaattcagatgaaagggactgtgggaggacaaaggcagtatgcacacggaagtataatcccatccctagtgtacagttgatgggcaatgggtttcattttctggcaggagagcccagaggagaagtccttgataactctttcactggaggaatatgtaaaactgtcaaaagcagtaggacaagtaatccataccgtgttccggccaatctggaaaatgtcggctttgaggtacaaactgcagaagatgacttgaaaacagatttctacaaggatttaacttctcttggacacaatgaaaatcaacaaggctcattctcaagtcagggggggagctctttcagtgtaccaattttttattcctcaaagagaagtgaaaatatcaaccataattctgccttcaaacaagccattcaagcctctcacaaaaaggattctagttttattaggatccataaagtgatgaaagtcttaaacttcacaacgaaagctaaagatctgcacctttctgatgtctttttgaaagcacttaaccatctgcctctagaatacaactctgctttgtacagccgaatattcgatgactttgggactcattacttcacctctggctccctgggaggcgtgtatgaccttctctatcagtttagcagtgaggaactaaagaactcaggtttaaccgaggaagaagccaaacactgtgtcaggattgaaacaaagaaacgcgttttatttgctaagaaaacaaaagtggaacataggtgcaccaccaacaagctgtcagagaaacatgaaggttcatttatacagggagcagagaaatccatatccctgattcgaggtggaaggagtgaatatggagcagctttggcatgggagaaagggagctctggtctggaggagaagacattttctgagtggttagaatcagtgaaggaaaatcctgctgtgattgactttgagcttgcccccatcgtggacttggtaagaaacatcccctgtgcagtgacaaaacggaacaacctcaggaaagctttgcaagagtatgcagccaagttcgatccttgccagtgtgctccatgccctaataatggccgacccaccctctcagggactgaatgtctgtgtgtgtgtcagagtggcacctatggtgagaactgtgagaaacagtctccagattataaatccaatgcagtagacggacagtggggttgttggtcttcctggagtacctgtgatgctacttataagagatcgagaacccgagaatgcaataatcctgccccccaacgaggagggaaacgctgtgagggggagaagcgacaagaggaagactgcacattttcaatcatggaaaacaatggacaaccatgtatcaatgatgatgaagaaatgaaagaggtcgatcttcctgagatagaagcagattccgggtgtcctcagccagttcctccagaaaatggatttatccggaatgaaaagcaactatacttggttggagaagatgttgaaatttcatgccttactggctttgaaactgttggataccagtacttcagatgcttaccagacgggacctggagacaaggggatgtggaatgccaacggacggagtgcatcaagccagttgtgcaggaagtcctgacaattacaccatttcagagattgtatagaattggtgaatccattgagctaacttgccccaaaggctttgttgttgctgggccatcaaggtacacatgccaggggaattcctggacaccacccatttcaaactctctcacctgtgaaaaagatactctaacaaaattaaaaggccattgtcagctgggacagaaacaatcaggatctgaatgcatttgtatgtctccagaagaagactgtagccatcattcagaagatctctgtgtgtttgacacagactccaacgattactttacttcacccgcttgtaagtttttggctgagaaatgtttaaataatcagcaactccattttctacatattggttcctgccaagacggccgccagttagaatggggtcttgaaaggacaagactttcatccaacagcacaaagaaagaatcctgtggctatgacacctgctatgactgggaaaaatgttcagcctccacttccaaatgtgtctgcctattgcccccacagtgcttcaagggtggaaaccaactctactgtgtcaaaatgggatcatcaacaagtgagaaaacattgaacatctgtgaagtgggaactataagatgtgcaaacaggaagatggaaatactgcatcctggaaagtgtttggcctag
Sequence Length
2805
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
104,786 Da
NCBI Official Full Name
Homo sapiens complement component 6, mRNA
NCBI Official Synonym Full Names
complement C6
NCBI Official Symbol
C6
NCBI Protein Information
complement component C6
UniProt Protein Name
Complement component C6
Protein Family
UniProt Gene Name
C6
UniProt Entry Name
CO6_HUMAN
NCBI Description
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]
Uniprot Description
C6: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C6 are the cause of complement component 6 deficiency (C6D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5p13
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: complement activation; regulation of complement activation
Disease: Complement Component 6 Deficiency
Research Articles on C6
Similar Products
Product Notes
The C6 c6 (Catalog #AAA1267367) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccagac gctctgtctt gtacttcatc ctgctgaatg ctctgatcaa caagggccaa gcctgcttct gtgatcacta tgcatggact cagtggacca gctgctcaaa aacttgcaat tctggaaccc agagcagaca cagacaaata gtagtagata agtactacca ggaaaacttt tgtgaacaga tttgcagcaa gcaggagact agagaatgta actggcaaag atgccccatc aactgcctcc tgggagattt tggaccatgg tcagactgtg acccttgtat tgaaaaacag tctaaagtta gatctgtctt gcgtcccagt cagtttgggg gacagccatg cactgagcct ctggtagcct ttcaaccatg cattccatct aagctctgca aaattgaaga ggctgactgc aagaataaat ttcgctgtga cagtggccgc tgcattgcca gaaagttaga atgcaatgga gaaaatgact gtggagacaa ttcagatgaa agggactgtg ggaggacaaa ggcagtatgc acacggaagt ataatcccat ccctagtgta cagttgatgg gcaatgggtt tcattttctg gcaggagagc ccagaggaga agtccttgat aactctttca ctggaggaat atgtaaaact gtcaaaagca gtaggacaag taatccatac cgtgttccgg ccaatctgga aaatgtcggc tttgaggtac aaactgcaga agatgacttg aaaacagatt tctacaagga tttaacttct cttggacaca atgaaaatca acaaggctca ttctcaagtc agggggggag ctctttcagt gtaccaattt tttattcctc aaagagaagt gaaaatatca accataattc tgccttcaaa caagccattc aagcctctca caaaaaggat tctagtttta ttaggatcca taaagtgatg aaagtcttaa acttcacaac gaaagctaaa gatctgcacc tttctgatgt ctttttgaaa gcacttaacc atctgcctct agaatacaac tctgctttgt acagccgaat attcgatgac tttgggactc attacttcac ctctggctcc ctgggaggcg tgtatgacct tctctatcag tttagcagtg aggaactaaa gaactcaggt ttaaccgagg aagaagccaa acactgtgtc aggattgaaa caaagaaacg cgttttattt gctaagaaaa caaaagtgga acataggtgc accaccaaca agctgtcaga gaaacatgaa ggttcattta tacagggagc agagaaatcc atatccctga ttcgaggtgg aaggagtgaa tatggagcag ctttggcatg ggagaaaggg agctctggtc tggaggagaa gacattttct gagtggttag aatcagtgaa ggaaaatcct gctgtgattg actttgagct tgcccccatc gtggacttgg taagaaacat cccctgtgca gtgacaaaac ggaacaacct caggaaagct ttgcaagagt atgcagccaa gttcgatcct tgccagtgtg ctccatgccc taataatggc cgacccaccc tctcagggac tgaatgtctg tgtgtgtgtc agagtggcac ctatggtgag aactgtgaga aacagtctcc agattataaa tccaatgcag tagacggaca gtggggttgt tggtcttcct ggagtacctg tgatgctact tataagagat cgagaacccg agaatgcaat aatcctgccc cccaacgagg agggaaacgc tgtgaggggg agaagcgaca agaggaagac tgcacatttt caatcatgga aaacaatgga caaccatgta tcaatgatga tgaagaaatg aaagaggtcg atcttcctga gatagaagca gattccgggt gtcctcagcc agttcctcca gaaaatggat ttatccggaa tgaaaagcaa ctatacttgg ttggagaaga tgttgaaatt tcatgcctta ctggctttga aactgttgga taccagtact tcagatgctt accagacggg acctggagac aaggggatgt ggaatgccaa cggacggagt gcatcaagcc agttgtgcag gaagtcctga caattacacc atttcagaga ttgtatagaa ttggtgaatc cattgagcta acttgcccca aaggctttgt tgttgctggg ccatcaaggt acacatgcca ggggaattcc tggacaccac ccatttcaaa ctctctcacc tgtgaaaaag atactctaac aaaattaaaa ggccattgtc agctgggaca gaaacaatca ggatctgaat gcatttgtat gtctccagaa gaagactgta gccatcattc agaagatctc tgtgtgtttg acacagactc caacgattac tttacttcac ccgcttgtaa gtttttggct gagaaatgtt taaataatca gcaactccat tttctacata ttggttcctg ccaagacggc cgccagttag aatggggtct tgaaaggaca agactttcat ccaacagcac aaagaaagaa tcctgtggct atgacacctg ctatgactgg gaaaaatgtt cagcctccac ttccaaatgt gtctgcctat tgcccccaca gtgcttcaag ggtggaaacc aactctactg tgtcaaaatg ggatcatcaa caagtgagaa aacattgaac atctgtgaag tgggaactat aagatgtgca aacaggaaga tggaaatact gcatcctgga aagtgtttgg cctag. It is sometimes possible for the material contained within the vial of "C6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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