ATOX1 cdna clone
ATOX1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
Uniprot Description
ATOX1: Could bind and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. Belongs to the ATX1 family.
Protein type: Transporter; Chaperone; Carrier
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: cytosol
Molecular Function: copper chaperone activity; copper ion binding; copper-dependent protein binding; metallochaperone activity; protein binding
Biological Process: copper ion transport; intracellular copper ion transport
Research Articles on ATOX1
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Product Notes
The ATOX1 atox1 (Catalog #AAA1266112) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCCGAAGC ACGAGTTCTC TGTGGACATG ACCTGTGGAG GCTGTGCTGA AGCTGTCTCT CGGGTCCTCA ATAAGCTTGG AGGAGTTAAG TATGACATTG ACCTGCCCAA CAAGAAGGTC TGCATTGAAT CTGAGCACAG CATGGACACT CTGCTTGCAA CCCTGAAGAA AACAGGAAAG ACTGTTTCCT ACCTTGGCCT TGAGTAG. It is sometimes possible for the material contained within the vial of "ATOX1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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