ASTL cdna clone
ASTL cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
ASTL: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding. Belongs to the peptidase M12A family.
Protein type: Protease; EC 3.4.-.-
Chromosomal Location of Human Ortholog: 2q11.1
Cellular Component: cytoplasm; plasma membrane
Molecular Function: metalloendopeptidase activity; peptidase activity
Biological Process: cell adhesion; fertilization; proteolysis
Research Articles on ASTL
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Product Notes
The ASTL astl (Catalog #AAA1273515) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGGGTG TAGGGGGTCT CTGGCCTTGG GTGCTGGGTC TGCTCTCCTT GCCAGGTGTG ATCCTAGGAG CGCCCCTGGC CTCCAGCTGC GCAGGAGCCT GTGGTACCAG CTTCCCAGAT GGCCTCACCC CTGAGGGAAC CCAGGCCTCC GGGGACAAGG ACATTCCTGC AATTAACCAA GGGCTCATCC TGGAAGAAAC CCCAGAGAGC AGCTTCCTCA TCGAGGGGGA CATCATCCGG CCGAGTCCCT TCCGACTGCT GTCAGCAACC AGCAACAAAT GGCCCATGGG TGGTAGTGGT GTCGTGGAGG TCCCCTTCCT GCTCTCCAGC AAGTACGATG AGCCCAGCCG CCAGGTCATC CTGGAGGCTC TTGCGGAGTT TGAACGTTCC ACGTGCATCA GGTTTGTCAC CTATCAGGAC CAGAGAGACT TCATTTCCAT CATCCCCATG TATGGGTGCT TCTCGAGTGT GGGGCGCAGT GGAGGGATGC AGGTGGTCTC CCTGGCGCCC ACGTGTCTCC AGAAGGGCCG GGGCATTGTC CTTCATGAGC TCATGCATGT GCTGGGCTTC TGGCACGAGC ACACGCGGGC CGACCGGGAC CGCTATATCC GTGTCAACTG GAACGAGATC CTGCCAGGCT TTGAAATCAA CTTCATCAAG TCTCGGAGCA GCAACATGCT GACGCCCTAT GACTACTCCT CTGTGATGCA CTATGGGAGG CTTGCCTTCA GCCGGCGTGG GCTGCCCACC ATCACACCAC TTTGGGCCCC CAGTGTCCAC ATCGGCCAGC GATGGAACCT GAGTGCCTCG GACATCACCC GGGTCCTCCA ACTCTACGGC TGCAGCCCAA GTGGCCCCAG GCCCCGTGGG AGAGGGTCCC ATGCCCACAG CACTGGTAGG AGCCCCGCTC CGGCCTCCCT ATCTCTGCAG CGGCTTTTGG AGGCACTGTC GGCGGAATCC AGGAGCCCCG ACCCCAGTGG TTCCAGTGCG GGAGGCCAGC CCGTTCCTGC AGGGCCTGGG GAGAGCCCAC ATGGGTGGGA GTCCCCTGCC CTGAAAAAGC TCAGTGCAGA GGCCTCGGCA AGGCAGCCTC AGACCCTGGC TTCCTCCCCA AGATCAAGGC CTGGAGCAGG TGCCCCCGGT GTTGCTCAGG AGCAGTCCTG GCTGGCCGGA GTGTCCACCA AGCCCACAGT CCCATCTTCA GAAGCAGGAA TCCAGCCAGT CCCTGTCCAG GGAAGCCCAG CTCTGCCAGG GGGCTGTGTA CCTAGAAATC ATTTCAAGGG GATGTCCGAA GATTAA. It is sometimes possible for the material contained within the vial of "ASTL, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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