Testing Data
Rabbit ASTL Polyclonal Antibody | anti-ASTL antibody
Anti-ASTL Antibody
Gene Names
ASTL; SAS1B
Reactivity
Human. Predicted: Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
ASTL; Polyclonal Antibody; Anti-ASTL Antibody; anti-ASTL antibody
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
1296
Applicable Applications for anti-ASTL antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user
Storage Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Immunogen
Rabbit polyclonal ASTL(1) antibody was raised against a recombinate human ASTL protein 228-407aa (BC107127).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
References
(1) Quesada,V., Sanchez,L.M., Alvarez,J. and Lopez-Otin,C..Identification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish. J. Biol. Chem. 279 (25), 26627-26634 (2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
45,936 Da
NCBI Official Full Name
Homo sapiens astacin-like metallo-endopeptidase (M12 family), mRNA
NCBI Official Synonym Full Names
astacin-like metallo-endopeptidase (M12 family)
NCBI Official Symbol
ASTL
NCBI Official Synonym Symbols
SAS1B
NCBI Protein Information
astacin-like metalloendopeptidase; ASTL; astacin-like metalloendopeptidase (M12 family); oocyte astacin; ovastacin; sperm acrosomal SLLP1 binding
UniProt Protein Name
Astacin-like metalloendopeptidase
Protein Family
UniProt Gene Name
ASTL
UniProt Entry Name
ASTL_HUMAN
Uniprot Description
ASTL: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding. Belongs to the peptidase M12A family.
Protein type: EC 3.4.-.-; Protease
Chromosomal Location of Human Ortholog: 2q11.1
Cellular Component: transport vesicle; cytoplasm; plasma membrane
Molecular Function: peptidase activity; zinc ion binding; metalloendopeptidase activity
Biological Process: fertilization; cell adhesion; proteolysis
Research Articles on ASTL
Similar Products
Product Notes
The ASTL astl (Catalog #AAA417725) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ASTL Antibody reacts with Human. Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ASTL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the ASTL astl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASTL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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