Typical Testing Data/Standard Curve (for reference only)
Mouse Cadherin-13 ELISA Kit | Cdh13 elisa kit
Mouse Cadherin-13 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The ELISA is based on the competitive binding enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen, During the reaction, target antigen in the sample or standard competes with a fixed amount of biotin-labeled target antigen for sites on a pre-coated antibody specific to target antigen. Excess conjugate and unbound sample or standard are washed from the plate. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. This gene is highly expressed in the vasculature including endothelial cells, smooth muscle cells and pericytes, where the encoded protein binds to adiponectin and has been implicated in the modulation of angiogenesis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Nov 2015]
Uniprot Description
CDH13: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, GPI anchor
Cellular Component: caveola; cytoplasm; external side of plasma membrane; extracellular space; focal adhesion; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane
Molecular Function: adiponectin binding; cadherin binding; calcium ion binding; low-density lipoprotein binding; metal ion binding; protein binding; protein homodimerization activity
Biological Process: calcium-dependent cell-cell adhesion; cell adhesion; endothelial cell migration; homophilic cell adhesion; keratinocyte proliferation; lamellipodium biogenesis; localization within membrane; low density lipoprotein mediated signaling; negative regulation of cell adhesion; negative regulation of cell proliferation; positive regulation of calcium-mediated signaling; positive regulation of cell migration; positive regulation of cell-matrix adhesion; positive regulation of endothelial cell proliferation; positive regulation of positive chemotaxis; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; Rac protein signal transduction; regulation of endocytosis; regulation of epidermal growth factor receptor signaling pathway; Rho protein signal transduction; sprouting angiogenesis
Research Articles on Cdh13
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Product Notes
The Mouse Cdh13 cdh13 (Catalog #AAA2883614) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883614 ELISA Kit recognizes Mouse Cdh13. It is sometimes possible for the material contained within the vial of "Cadherin-13, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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