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SDS-PAGE

CD300C / CMRF-35 / IGSF16 recombinant protein

Recombinant Human CD300C / CMRF-35 / IGSF16 Protein (His tag)

Gene Names
CD300C; LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CD300C / CMRF-35 / IGSF16; Recombinant Human CD300C / CMRF-35 / IGSF16 Protein (His tag); CLM-6; CMRF-35; CMRF-35A; CMRF35; CMRF35-A1; CMRF35A; CMRF35A1; IGSF16; LIR; CD300C / CMRF-35 / IGSF16 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
224
Application Notes
The recombinant human CD300C consists of 166 amino acids and predictes a molecular mass of 18.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CD300C is approximately 40-45 kDa due to glycosylation.
Predicted N Terminal
Met 29
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for CD300C / CMRF-35 / IGSF16 recombinant protein
Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD300 is a glycoprotein family of cell surface molecules that regulate a diverse array of cell processes via their triggering and inhibitory receptor functions. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as CD300c and CD300d, whose function is uncertain.

Description: A DNA sequence encoding the human CD300C (NP_006669.1) extracellular domain (Met 1-Arg 183) was expressed, with a polyhistidine tag at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,830 Da
NCBI Official Full Name
CMRF35-like molecule 6
NCBI Official Synonym Full Names
CD300c molecule
NCBI Official Symbol
CD300C
NCBI Official Synonym Symbols
LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1
NCBI Protein Information
CMRF35-like molecule 6
UniProt Protein Name
CMRF35-like molecule 6
UniProt Gene Name
CD300C
UniProt Synonym Gene Names
CMRF35; CMRF35A; CMRF35A1; IGSF16; CLM-6; CMRF-35; IgSF16

NCBI Description

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]

Uniprot Description

CD300C: Belongs to the CD300 family

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: cellular defense response; regulation of immune response

Research Articles on CD300C / CMRF-35 / IGSF16

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Product Notes

The CD300C / CMRF-35 / IGSF16 cd300c (Catalog #AAA2545655) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human CD300C consists of 166 amino acids and predictes a molecular mass of 18.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CD300C is approximately 40-45 kDa due to glycosylation. Researchers should empirically determine the suitability of the CD300C / CMRF-35 / IGSF16 cd300c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD300C / CMRF-35 / IGSF16, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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