CD200R4 recombinant protein

CD200R4 Protein, Mouse, Recombinant (His Tag)

Cat. Num. AAA8122883

• Gene Names: Cd200r4; MCD200RLa; F630107N04Rik
• Purity: >96% as determined by SDS-PAGE
• Synonyms: CD200R4; CD200R4 Protein; Mouse; Recombinant (His Tag); Mouse CD200R4/CD200 Receptor 4/CD200RLa Protein (His Tag); Cd200r4 Protein; F630107N04Rik Protein; MCD200RLa Protein; CD200 receptor 4; CD200R4 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >96% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Thr241

• Species: Mouse
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Thr 26
• Tag: C-His
• Protein Construction: A DNA sequence encoding the extracellular domain of mouse CD200R4 (NP_997127.1)(Met 1-Thr 241) was expressed, fused with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for CD200R4 recombinant protein

Background: Cell surface glycoprotein CD2 receptor 4, also known as Cell surface glycoprotein OX2 receptor 4, CD2 cell surface glycoprotein receptor-like 4, CD2RLa, and CD2R4, is a single-pass type I membrane protein which belongs to theCD2R family. CD2 (OX2) is a cell surface glycoprotein that interacts with a structurally related receptor (CD2R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. In mouse there are up to five genes related to CD2R with conflicting data as to whether they bind CD2. CD2R4 contains oneIg-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. CD2R4 is highly expressed in monocytes, NK cells and a subset of NKT cells. It is weakly expressed in granulocytes and B cells (at protein level). CD2R4 is also expressed in brain, lung, testis, thymus, intestine and uterus. and in bone marrow derived-macrophage and dendritic cells and mast cells. CD2R4 is involved in the recruitment or surface expression of the TYROBP receptor.

References

Wright, GJ. et al.,2003, J. Immunol. 171: 3034-46. Gorczynski, R. et al., 2004,J. Immunol. 172:7744-7749. Gorczynski, RM. et al.,2004, Am. J. Reprod. Immunol. 52:147-163. Hatherley, D. et al.,2005. J. Immunol. 175: 2469-2474.

NCBI and Uniprot Product Information

• NCBI GI #: 46402237
• NCBI GeneID: 239849
• NCBI Accession #: NP_997127.1
• NCBI GenBank Nucleotide #: NM_207244.2
• UniProt Accession #: Q6XJV4
• Molecular Weight: 29,625 Da
• NCBI Official Full Name: cell surface glycoprotein CD200 receptor 4
• NCBI Official Synonym Full Names: CD200 receptor 4
• NCBI Official Symbol: Cd200r4
• NCBI Official Synonym Symbols: MCD200RLa; F630107N04Rik
• NCBI Protein Information: cell surface glycoprotein CD200 receptor 4
• UniProt Protein Name: Cell surface glycoprotein CD200 receptor 4
• Protein Family: Cell surface glycoprotein CD200 receptor
• UniProt Gene Name: Cd200r4
• UniProt Synonym Gene Names: CD200 receptor-like 4; CD200RLa

Uniprot Description

Involved in the recruitment or surface expression of the TYROBP receptor.